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Understanding Nutrient Sequestration in Skin Rash Diseases

Posted By Jennifer Shipp | Jul 27, 2026

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Liver Disease, Skin Disease, and Fever: How Fat-Soluble Vitamin Sequestration Leads to Diseases Involving Skin Rash and Fever

The liver always plays a central role in detoxification of the body, but it is also an important organ that can contribute to the production of a fever. In Traditional Chinese Medicine (TCM), Liver Fire and Liver Qi Stagnation are two different issues with the movement of energy (qi or chi) in the body that lead to fever. Infectious pathogens of various types (bacteria, amoeba, viruses, protozoa, parasites, etc.) can infect the liver to cause febrile illness. Indeed, fatty liver disease and the excess buildup of fats in the liver can also set off a fever along with other symptoms.

Let’s look at a fever as a pathological form of heat production in the body. There are other types of heat production though that are not pathological. The body produces more than the usual amount of heat when it is very active, such as during exercise, for example. And in some Tibetan monasteries, monks dedicate their entire lives to a special practice that involves going into a very cold environment to use breath and visualization (with cold, wet sheets draped over their backs) to raise their body temperature by up to 17°C / 62°F. This practice, known as “Tummo” in Tibetan, has been studied by scientists to demonstrate that novices can also raise their body temperature using the same breath, posture, and visualization strategy (though participants raise their body temperature by less than those who have spent their entire lives practicing Tummo).

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We discuss neurotransmitters like norepinephrine and the involvement of the sympathetic nervous system in brown fat activation for heat production elsewhere, but the focal point here is the liver. There is a brain-liver-sympathetic nervous system-brown fat axis that has been identified by scientists through which these particular areas of the body can be accessed and rebalanced using cold exposure therapy, similar to the cold exposure that Tibetan monks are doing in order to gain conscious control over heat production in their bodies. Most people are not interested in dedicating their lives to being able to consciously raise their body temperature by altering norepinephrine physiology using visualization, cold exposure, and breath, but a lot of people today are interested in rebalancing the brain-liver-brown fat-sympathetic nervous system axis for the purposes of restoring health in situations that seem very hopeless according to conventional medicine.

So in this section of our discussion, I want to discuss the liver in greater depth, as well as the skin as an organ that often produces a rash when the liver is overwhelmed by toxins, fat buildup, or low-level pathogenic infection. There are situations in which the liver is overwhelmed by a pathogenic infection that produces symptoms of acute infection (high fever, nausea, vomiting, diarrhea, respiratory symptoms, etc.). The liver ends up being a focal point during infection because of its detoxification role in removing toxins that are produced by pathogens, but after the acute stage of an infection ends, the liver is often headquarters to pathogens that have managed to survive immune system assaults, antibiotic treatments, and the usual efforts that humans today make in order to overcome an infection. A common symptom of liver issues is rash or skin-related changes because the liver is intimately connected to the skin and the skin depends on the liver for fat-soluble vitamins, among other things for its health. 

A sick, jaundiced liver will produce a yellowing of the skin and the whites of the eyes or various manifestations of skin rash. Psoriasis is a famous skin rash that develops in response to the body’s inability to off-load toxins via the liver or the kidneys. Dead Sea soaking with sunlight exposure is a famous cure for psoriasis that works through the skin-liver connection, healing the disease through a combination of sunlight exposure to produce fumaric acid in the skin along with natural vitamin D, and trace mineral exposure through the skin. Psoriasis patients almost always suffer from fairly severe digestive system issues that are often not diagnosed as a part of the psoriasis package in conventional medicine, leading psoriasis patients to believe that their skin rash is separate from and not related to their digestive system issues. But, in fact, soaking in the Dead Sea (and in other ocean waters with sunlight exposure) is effective, at least in part, because the body can absorb trace minerals through the skin when the digestive system is too inflamed to be able to absorb these healing elements. 

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We’ve already discussed the somewhat miraculous healing effects of low-dose alcohol administration (particularly red wine or whiskey) in children and adults with intermittent low-grade fever or even high-grade fevers that are due to infection or that are psychogenic in origin. Certain types of alcohol have been in use for centuries by doctors who knew how to cure diphtheria, for example, via the use of alcohol like whiskey or red wine that contains zinc, iron, and copper together along with other trace minerals. In low doses, alcohol makes nutrients and medicinal agents more easy to absorb in the digestive system. And when combined with alcohol, these trace nutrients are able to more easily find their way into cells, even in the face of insulin resistance. Alcohol administered in low doses, after all, can substitute for insulin in the body and for serotonin in the brain. In higher doses, the cells tend to react to alcohol as a poison, so low-dosing is key and we’ll talk more about that later. But for now, let’s just give a nod to alcohol as a substance that acts as a medicine in low doses and a substance that can be toxic in high doses, particularly for those in a hot climate.

Regular Wim-Hof-style cold exposure can alter how the body processes alcohol, exerting a protective effect on the liver against fatty liver disease and cirrhosis. This change that takes place through a liver-brain / sympathetic nervous system-brown-fat axis, alters insulin sensitivity as well as fat-allocation patterns in the body. Essentially, an overheated or chronically warm body that is rarely, if ever, exposed to a cold environment that challenges the sympathetic nervous system (with provocative effects on brown adipose tissue, spurring conversions of white fats to brown fats), will be prone to insulin-related health issues. I say “insulin-related issues” rather than just talking about diabetes because alcoholism is also an “insulin-related health issue”. Autism / ASD is an “insulin-related health issue” as is Attention Deficit Hyperactivity Disorder / ADHD, cancer, and more

In regard to autism and “insulin-related issues”, I refer the reader to material by Dr. Naviaux, the doctor who successfully use Suramin to cure ASD / autism. He developed the model of the Cell Danger Response which takes us down the rabbit hole of cachexia (wasting disease) and Resignation Syndrome. Resignation Syndrome is a situation that’s triggered by an emotional trauma. Our focus here, in fact, is fevers so I refer readers to our discussion of psychogenic fever to fully circumnavigate the existing data on this topic, but in Resignation Syndrome, fever may or may not be present. Yet the patient falls slowly into a coma as a result of an emotional trauma as a way for a person, usually a dependent adult or child, to stay in a twilight consciousness, barely clinging to life, in a state of strict energy-conservation. These individuals are often still conscious, though they are non-communicative, and, at least in the case of Swedish refugee children whose families are sentenced to return to desperate situations in their country-of-origin, the children often come out of their comatose state when parents report that they’ve been given permission to stay in the safe country.

In the body, insulin is a hormone that carries sugars, but also amino acids, and fatty acids into cells. It is a gatekeeper who has special access among the other hormones (with the exception of serotonin in the brain) to open cells and provide them not just with nutrients but also sometimes medicines. But insulin must come in peace, or else cells become insulin resistant. If cells are overloaded with too much exposure to insulin knocking at their door, they begin to refuse to open up. The more insulin-resistant a body becomes, the more lethargic and sick the body becomes in response. All of those nutrients need to go somewhere or they get released through defecation or urination as in the case of life-giving minerals like iron, zinc, copper, or iodine. Nutrients like fat-soluble vitamins, which can be stored in the body and they can build up in the liver when a mood of insulin resistance begins to grip cells. Emotional trauma can cause all of this to happen. This is an established fact that has been observed in the Swedish refugee children who have fallen into a swoon of Resignation Syndrome, lying inert with feeding tubes in dark bedrooms as their families wait to find out if the sponsoring government will force them out with their sick child or grant them the opportunity to stay. 

Diabetes is a disease that’s most famous as an “insulin-related health issue”. In an effort to produce mass confusion, conventional medicine differentiates between two types of diabetes. Type 1 diabetes is regarded as a disease of insulin-production. In type 1 diabetes, the pancreas is not producing enough insulin, or so the rhetoric goes. In type 2 diabetes, cells are insulin resistant. There is a type 3 diabetes, but it only adds to the confusion when, in fact, all forms of diabetes involve some combination of low pancreatic production of insulin combined with insulin resistance in cells.

…but in reality, everyone who is able to sleep well becomes “temporarily diabetic” for a period of time each night during Rapid Eye Movement (REM) sleep. During REM sleep, the body stops releasing insulin. This is a time when the body releases a part of the soul (maybe not all parts of the soul) into another realm of our reality, namely The Dream World. The Dream World is more than one place, but this lack of insulin release while dreaming cues the body to release Growth Hormone instead. Growth Hormone is necessary in order for the body to repair itself day-by-day. So we might say that Growth Hormone is like an architect that draws up the blueprints for our bodies (while insulin takes a much-needed break), inserting impulses and motivation into our autonomic nervous system and the endocrine system to guide us through each day. Back-and-forth eye movements that are identical, yet physiologically slightly different from the daytime trauma-releasing therapy known as Eye Movement Desensitization and Reprocessing (EMDR) are part of REM sleep, Growth Hormone release, and the temporary state of diabetes produced by the silencing of insulin during this state of dreaming and blueprint development and processing that’s based on the most challenging aspects of the previous 2-3 days of our lives.

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Now, at this point, dear reader, you might feel like revolting against my asserting that the body is sending soul parts away into a Netherworld of Dreams and I would understand this because we have been taught in an unconditional way to regard the body and the mind as separate. We are also taught to tread very carefully into spirituality as an experience that is unverifiable and possibly false, or at least irrelevant in the scientific realm. But in order to maintain that stance, we have to ignore centuries of soul retrievals by shaman throughout the world as some of the most important medicinal treatments that have existed to maintain the human race. And you will also have to ignore the fact that people with multiple personality disorder (also known as dissociative identity disorder / DID) have been studied scientifically for their ability to have diabetes and to also not have diabetes. Essentially, one sub-personality (read: soul part) in an individual with multiple personality disorder / DID can have diabetes while a different sub-personality (in the same patient) does not have diabetes. So, here we have a situation in which a person can embody one soul part that has diabetes at one time of the day (not during the normal time of night when people become temporarily diabetic) and then they embody a different soul part at another time of day and they are not diabetic according to scientists.

An ancient human being who belongs to a nomadic tribe does not have the same psychology as a modern human. This is not to say that one type of psychology is better than another type of psychology. Rather, I ascribe to the idea that whatever challenges us to develop new ways of being human is always directed by Beings of Light toward positive outcomes. But for modern humans, the Christian Era / C. E. was a time when the major religions began to demand soul loss as a way to stay alive and avoid being burnt at the stake. At that time, the most prominent institutions had not been developed fully yet. Government and religion were not separate things. Through the horrifying experience of the Spanish Inquisition and other genocidal movements, the human race learned and (is still sadly learning) about how the imposition of government on religion and religion on government creates pain for everyone, sparing no one.

Nonetheless, the Soul Loss (and the inability to call the soul back) suffered by our ancestors as a result of the Christian Era, is directly related to the most current form of chronic disease. In TCM, the liver is the organ of anger. And in the psychology model that is most closely related to these ideas about soul loss and sub-personalities, Internal Family Systems, Dr. Richard Schwartz details how Anger is an emotion that can be embodied as a sub-personality that walks, talks, and thinks independently of other facets of an emotionally traumatic experience. Anger stands guard in defense of the other, more vulnerable facets, the sub-personalities that the psyche breaks into, like a puzzle that can be “reintegrated” through certain trauma-informed therapies to restore the original, unblemished story of a traumatic event. When a modern human psyche fractures, it breaks into various, sometimes a multitude of parts, each of which are packages of emotion

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It is an established fact that humans use emotion to make decisions, even decisions that seem to be based on “logic”. In fact, we make decisions using emotions, but we justify our decisions using logic. In education, emotion similarly acts as a foundation. We pack informational bits into backpacks made up of emotions. Memorization of facts is unlikely to yield a lasting, internal-encyclopedia of information that an individual can access. Rather, we “memorize” information naturally and we develop a full understanding of a body of knowledge when we’re interested and when we care about it. 

Further, narrative and stories are the basic unit of human experience. But when a person loses their personal narrative and the ancestral trajectory - their family history, it can be incredibly hard to feel interested in any data set. 

We’re pretty far afield, at this point, from where we started in discussing the liver, skin disease, and fevers. How does all of this relate to fatty liver disease and the sequestration of fat soluble vitamins in the liver? Maybe you’re an adult with a chronic skin disease or maybe you’re the parent of a child with eczema or an infection that produces a rash. No matter whether you’re chronically ill and an adult or whether you’re trying to figure out how to confront a major childhood infection like measles or hand, foot, and mouth disease as a parent, it’s important to recognize that the body will sequester nutrients like iron or fat-soluble vitamins in response to a trauma, either emotional or biological. And in order to speak about biological trauma, it’s important to pay homage to the chicken-or-the-egg problem of heat and cold. It may or may not be possible for a person to get rid of pathogens in an absolute sense like Streptococcus pyogenes or Coxsackievirus (to name just two pathogens from a very long list of them), but if we are all host to certain pathogens, perhaps from before we’re even born and if there is no way to disentangle our lives from the lives of some of these commensal organisms, then we have to still ask ourselves how we can, at the very least, gain the upper hand and be in control of the situation. 

In order to be in control of ourselves and our bodies as modern humans who live in a fractured society that requires us to interact with institutions that demand very contrasting allegiances to rules that we must follow as hypocrites, in order to survive, we have to understand logically what’s happening inside the body. This is how modern humans are built. We are not one soul in one body. We are multiple soul parts, cliques of soul parts that have been mercilessly fractured and sent to different part of The Dream World and even after we integrate these soul parts and make them all fit together so that they can coexist within the same body by using the varied forms of trauma-informed therapies that exist, we are still faceted (though we’re in far less pain and we then have facets as a resource). There’s nothing wrong with having this kind of psychology, but we can appreciate the fact that other societies that are less fragmented and that require less hypocrisy produce a different, albeit still beautiful psychology that’s entirely functional in societies that have not been broken by unwieldy governments and uncompromising religious institutions.

So let’s rewind and go back to the initial part of this discussion where we were talking about insulin and temporary states of diabetes in which the insulin release shuts down completely so that Growth Hormone can release parts of our energy field to wander in other realms. During these states, we become temporarily for short bursts of time, like the Resignation Syndrome children who describe their comatose state as an experience in which they are trapped in a fragile glass cube filled with water. Even the tiniest movement or flinch might break that cube and release the entirety of their soul as a whole unit into the watery, emotional nature of the Dream Realm. But in short bursts in the middle of the night during REM sleep states, we release our energies as soul parts or sub-personalities into The Dream Realm of the unconscious. Insulin shuts down as the metaphorical general contractor for human cells, allowing construction and repair to pause briefly so that our energies can be used instead to come up with the blueprint for restoration and rejuvenation through the action of Growth Hormone.

In the liver, insulin normally dominates the regulation of glucose production in a healthy mammal, at least in animal models of liver disease. In the liver, insulin prevents the production of glucose and instead, promotes the de novo production of fats and, at least, in some cases, a build up of fats in the liver (i.e. fatty liver disease). When an individual becomes insulin resistant outside of that nightly Dream Time exploration when Growth Hormone takes over, glucose production continues on in an unrestrained manner along with lipid and fat production in the liver.

The scientific community is on the fence regarding the issue of how insulin regulates lipid and fat production in the liver. In individuals who have cellular insulin resistance, blocking insulin signaling reduces lipid and fat deposition in the liver suggesting that insulin regulates lipid metabolism. This issue is an important one for diabetics because most diabetics inject their synthetic prescription insulin peripherally, often in the legs rather than injecting insulin into the central part of the body where insulin is naturally produced and released by the pancreas. Studies suggest that this practice of injecting insulin peripherally fails to signal the liver to react appropriately, leading to fatty liver disease, sequestration of fat soluble vitamins, and damage to the body as a whole as a result. During an insulin resistant state that happens in disease outside of that natural status of temporary diabetes during REM sleep cycles and a milieu of Growth Hormone, the liver responds differently than it does to insulin resistance that occurs outside of this deep-sleep state combined with Growth Hormone release.

In TCM, the liver’s peak time for restoration and rejuvenation is between 1:00 AM and 3:00 AM. This time is known as Chou Shi and it is critical as a time of night for deep sleep when the liver detoxifies, repairs itself, and blood is regenerated. Wakefulness during this time of night suggests either stagnation or excess heat in the liver, an imbalance that indicates that disease is in progress. 

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Let’s compare the idea of liver rejuvenation specifically (all of the organs have a special time of night when they rest and repair themselves in TCM) with data about REM sleep cycles which produce a state of rest in regard to insulin release combined with Growth Hormone release instead. REM sleep cycles tend to start about 90 minutes after a person falls asleep. The first REM episode typically lasts only about 10 minutes. After that, REM sleep cycles happen again 4 to 6 times throughout the night, becoming progressively longer. Most REM sleep happens during the “Second Sleep” part of the night (which happens after a natural cortisol surge around 3:00 AM when people often wake up for a little while for lighter sleep, or restful, but wakeful contemplation), with the final, longest episode of REM sleep lasting about an hour during a good night of sleep.

REM sleep cycles align with the wisdom of the TCM body clock which focuses on detoxification and the processing of emotions most powerfully between 1:00 AM and 5:00 AM. Between 1:00 and 3:00 AM, the liver detoxifies and processes emotional stressors that include anger, frustration, and chronic stress. The lungs detoxify and process negative emotions between 3:00 and 5:00 AM. The liver, as holder of angry emotions and the emotions of self-defense, detoxifies during one of the most powerful times of the night in terms of REM sleep. The lungs, as holders of grief and the emotions of a broken heart, detoxifies and processes these emotions in the wee hours of morning when REM sleep cycles are gaining steam. The other night-time organs that detoxify during sleep states at night are the Triple Burner (between 9:00 PM and 11:00 PM), the gallbladder as the holder of ancestral trauma and decision-making capabilities (between 11:00 PM and 1:00 AM), and the large intestine as the organ that prepares to eliminate toxins during the last stages of sleep in the morning (5:00 AM to 7:00 AM).

The various organs of the body act as representatives for different emotional states, an idea that was set forth by TCM, and REM sleep states create an opportunity for those organs to be repaired through Growth Hormone release and the corresponding release of parts of our energy field into realms of healing. But if we have been psychically fractured, as most modern humans have, and if our psychology includes cliques of emotion-based sub-personalities / soul parts with anger at the front, standing sentinel in self-defense, we can then go back to the idea of fat-soluble vitamin sequestration in the liver as a biological metaphor for defensive hoarding of these nutrients. Anthropomorphizing the liver as a soldier that marches on despite some of the most incredible insults and injuries is helpful. Male or female, the liver is the part of us that stands watch against whatever might try to steal our sense of safety in the world. Fat-soluble sequestration in the liver is a biological safeguard when it is a temporary condition, but it is a devastating insult against our own internal ecological balance

You can harvest fossil fuels and store them and even use them to the benefit of humanity just as the liver can harvest fat-soluble vitamins and store them for the use and benefit of all organs of the body, but if that process of harvest and storage becomes greedy or imbalanced, problems arise.

If the liver begins to sequester fat-soluble vitamins in a more long-term manner, refusing to release them into the body so that other organs can use them, the skin shows signs of this defensive stance first. The skin might turn yellow (a bile related issue), blue (lack of oxygen), or even green / grey (an issue related to bile) in response to what the liver is doing. As the skin changes color, its interaction with different wavelengths of light from the sun (which is full-spectrum light) is altered. This change is important because our bodies were designed to interact with the sun as a source of healing. Covering up with sunscreen and heavy clothes can be devastating in this regard.

A liver that is sequestering fat-soluble vitamins is holding nutrients captive. You might be eating the healthiest diet on the planet and taking supplements four times per day, but your liver hoards these stores on behalf of your most toxic, angry, and defensive emotions.

Now, let’s go back to the problem of Streptococcus pyogenes and other iron-loving pathogens. As the liver hoards fat-soluble vitamins, it gets sicker and sicker. Maybe an individual with a fatty liver like this is exposed to an externally introduced pathogen, or perhaps that individual has a very controlled infection in the body already when the liver hits critical mass. In any case, at some point, the liver reaches a tipping point and an iron-loving pathogen takes hold. A mildly or severely diseased liver is the perfect piece of real estate for an iron-loving pathogen. And once this pathogen gets enough of a foothold in the diseased liver, the autonomic nervous system sounds an alarm to activate the immune-based mononuclear phagocyte system to claim the iron for protection. Iron, after all, is like gold inside the body.  

Once this shift happens, a battle ensues for iron-resources as the most vital currency. Red blood cells are damaged. Thyroid hormones become inert, ultimately alerting the thyroid gland to potential threats. Brain fog ensues. The human organism becomes lethargic and disorganized in mounting an effort against the disease. Until the liver can process and release its anger as heat (read: fever) or its sense of learned helplessness (a depression born of anger turned inward) as stagnation of energy, there are no supplements, no medicines that can change the trajectory of the disease process fully. Trauma-informed therapies combined with intentional cold exposure (and sometimes also high heat exposure) are the starting block.

Alcohol administration in low doses can be helpful if it is properly administered in a medicinal way to reduce liver heat. We all know that heavy drinkers tend to come in two forms: the angry drunk and the depressed drunk. Heavy drinking brings the traumatized sub-personality of the liver forward if underlying traumas have not been properly processed. In order to shift the hoarding nature of the liver while also shifting iron stores back into general circulation (as opposed to having it under the strict control of the mononuclear phagocytic system), alcohol is vital. Insulin resistance is always a problem once the liver starts hoarding the fat-soluble vitamins. The cells and the body as a whole, holographic representative for its cells, is refusing to take in new, nutritious minerals and nutrients. Supplements won’t help. A good diet won’t help. Once this situation takes shape, you have to work with specific treatments to overcome it.

Resources:
Walker, N. F. and Chiodini, P. L. (2018). Liver lesions in the returning traveler.
Retrieved February 20, 2026 from https://www.sciencedirect.com/science/article/abs/pii/S1357303917302785#:~:text=Symptoms%20suggestive%20of%20a%20liver,may%20be%20the%20only%20sign

U.S. Department of Veteran Affairs (n.d.). Liver Disease.Retrieved February 20, 2026 from https://www.hepatitis.va.gov/basics/liver-disease-symptoms.asp 

Benson, H. et al. (1982). Body temperature changes during the practice of g Tum-mo yoga. Retrieved February 20, 2026 from https://ui.adsabs.harvard.edu/abs/1982Natur.295..234B 

Zunin, I. D. et al. (2025). Effects of Tummo Meditation and Niguma Yoga on Brain Activity. Retrieved February 20, 2026 from https://pmc.ncbi.nlm.nih.gov/articles/PMC12679118/#:~:text=Following%20Tummo%20and%20Niguma%2C%20a,in%20alpha%20percent%20power%20reported

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