DMSO for Down Syndrome: The Actual Story

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In 1959, dimethyl sulfoxide, also known as DMSO, was researched for its ability to protect cells and tissues from the damaging effects of freezing temperatures. In 1963, Dr. Stanley Jacob was working in a cryogenics lab and he began working with DMSO to hasten the healing process for strains and sprains. He also worked with DMSO to treat arthritis. Dr. Jacob was also one of the most important doctors to study, observe, and then promote the miraculous healing effects that DMSO could have on the brain and the nervous system. He administered massive doses of DMSO intravenously in patients with spinal cord injuries and found that DMSO promotes nervous system tissue healing. Patients with severe spinal cord injuries that would normally result in either death or paralysis were often able to move and walk again with DMSO therapy. 

But before Dr. Stanley Jacob began working with DMSO in medical settings, Dr. Nicholas Weinstein made use of DMSO and amino acids to reverse Down syndrome symptoms in hospitals in Chile and Argentina. His work with DMSO and amino acids for Down syndrome began during World War II after he fled the Hitler regime and settled in Chile. Today, the Calvo MacKenna Hospital in Santiago, Chile still works with his DMSO Down syndrome treatment to improve Down syndrome outcomes.

After DMSO was approved by the FDA in the United States for use during pregnancy to treat bladder irritation (also known as cystitis), the FDA and Big Pharma realized that Dr. Jacob’s use of DMSO was a threat to the conventional medicine industry that serves those with chronic, lasting damage from traumatic injury. Thus, the FDA and Big Pharma sought to restrict the use of DMSO and prevent people from knowing about or understanding how to use DMSO. Animal studies were contrived and heavily publicized to show that DMSO caused changes in the lens of the eye, but research could never prove that lasting eye lens changes occurred in humans who were given DMSO.

Since that time, studies have been done on patients with Down syndrome to determine whether or not DMSO can be useful in treating this disease. DMSO has several properties that indicate that it might be useful as an at-home treatment for Down syndrome. These properties include:

• DMSO enhances skin penetration. 
• DMSO easily passes the blood-brain-barrier.
• DMSO combines with certain substances (such as nutrients) to carry them through tissues or the blood-brain-barrier when normally those substances would not be able to pass. Some scientists have used DMSO in combination with nutrients like amino acids, vitamins, or minerals to deliver these nutrients more effectively to the brain in those with Down syndrome or learning disability.
• DMSO opens the small blood vessels / capillaries to enhance blood flow and oxygenation of tissues in areas that have been closed off from blood flow due to injury or infection.
• DMSO is a pain-killer that inhibits prostaglandins.
• DMSO reduces inflammation.
• DMSO is a diuretic.
• DMSO has been used successfully to heal brain trauma and spinal cord trauma that would otherwise be unable to heal. 
• DMSO has been used to treat Alzheimer’s disease and to remove amyloid deposits in the brain. The development of early Alzheimer’s disease is a common problem for those with Down syndrome so this ability to remove amyloid deposits is particularly noteworthy.

Click here to buy pharmaceutical grade dimethyl sulfoxide.

DMSO has been given to adult humans without any serious adverse effects at a dose of up to 1 gram per kilogram of the patient’s body weight. At an intravenous dose of 1 gram per kilogram of body weight DMSO does cause some hemolysis (rupture) of red blood cells, but this does not generally pose major health issues at this dose.

At doses above 1 gram / kilogram body weight, adult human patients may experience liver, kidney, or intestinal damage according to some sources. Children have not been studied as extensively in terms of the dose or possible adverse effects using DMSO, however, this is true of most pharmaceuticals. Nonetheless, this deserves mention. 

Regular, pharmaceutical-grade DMSO causes an intense oyster-like body odor. There are low-odor DMSO products available on the market. Those who spend a lot of time with someone who is being given DMSO can take a small amount of DMSO (a few drops) themselves to make the smell less noticeable and more tolerable. Check with your doctor if you are taking medications before you administer DMSO.

In adults, some of the minor side effects associated with DMSO administration at a dose of 1 gram / kilogram of body weight (or less) include:

• Breath or body odor resembling garlic or oysters
• Very dry, leathery, red skin (when DMSO is applied topically)
• Mild sedation
• Headache
• Dizziness
• Nausea

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Nutrient Therapy and DMSO for Down’s Syndrome: Chilean Research

In 1975, doctors in Chili gathered 31 young Down syndrome patients to study the effects of combining DMSO with the following nutrients:

• GABA
• GABOB
• N-Acetyl-L-Glutamine
• L-Arginine

Click here to buy pure GABA powder that can be mixed with DMSO.

These nutrients were administered intramuscularly either daily or every other day (depending on the child’s age) with DMSO. These intramuscular injections were carried out for 90 days. The children were then given a rest period of 30 days during which time they were given the amino acids orally without DMSO or any type of injection.

These cycles involving the administration of intramuscular injections followed by oral administration of amino acids were carried out 3-5 times in total depending on the child’s age.

Click here to buy pure L-Arginine powder. 

Each child’s response to the treatment was monitored using:

• Lab tests
• Psychometric tests (to measure cognitive performance changes)
• Physical exams

Though this was not a double-blind study because of the body odor caused by DMSO (which means that researchers could tell which participants were given DMSO and which ones were not), there was a control group of 24 Down syndrome children who did not receive any form of treatment. The scientific establishment contends that the positive results of this study weren’t viable because researchers could tell which patients were being treated (due to the strong body odor caused by DMSO) and which ones were not. However, though there were photos taken of every child, these photos weren’t published in the research and though there physical measurements taken of the children, these also were not published. The authors of the research study also stated that they wanted to continue treatment with DMSO and amino acids for at least 2 years to attain better results. But there were no follow-up studies done by the researchers. It seems likely that, like Dr. Henry Turkel and many other doctors and scientists before him who had discovered cures for serious diseases (read: extremely profitable diseases), the scientists were bullied into not heavily publicizing their work for fear of losing their licenses to practice medicine or some other type of political form of “burning-at-the-stake”. In Latin American countries, representatives of Big Pharma often go directly to doctors and threaten them with the loss of their licenses. A good example of political bullying of this nature in Latin America happened in Brazil where doctors began administering Tabebuia impetiginosa / Handroanthus impetiginosus bark to cure cancer successfully in hospitals. Even as people gathered in groups outside the hospital for treatment with Tabebuia impetiginosa, these doctors were threatened by U.S. representatives from Big Pharma and sadly, they stopped using the bark to cure cancer. 

Click here to buy N-Acetyl-L-Glutamine.

Because Down syndrome is a very profitable industry for Big Pharma, scientific studies must be viewed through a political lens to tease apart what’s likely true and what’s likely false. DMSO has the ability to heal the brain and nervous system as demonstrated through Dr. Stanley Jacob’s work with traumatic brain and spinal cord injuries, but studies into the use of DMSO for Down syndrome seem to have been stymied and then hidden using specific political tactics that make the general public wish to turn a blind eye to them. Treatment centers using DMSO and amino acids for Down syndrome are located in countries outside of the United States because the FDA shuts down facilities that cure major diseases inside the United States.

According to a Chilean study, in Down’s syndrome children under 3 ½ years of age, physical attributes of patients who were treated using DMSO and amino acids changed during the course of treatment. Specifically, the epicanthal folds at the corners of the eyes began to disappear, hair thickened, and the characteristic appearance of the nasal bridge began to change. Children of all ages who completed this study showed improvements in motor skills and social skills. Below we give more information about studies conducted on DMSO and amino acids.

It should be noted that one minor side effect of this form of treatment were non-painful, temporary, hard nodes at the injection site. Some children also developed a skin rash that went away after treatment.

The Chilean doctors who worked to cure Down’s syndrome children and alleviate some of their symptoms said that it would be necessary to do treatment cycles for at least 2 years to see dramatic and lasting changes, however, after the initial injections are done, parents can take the supplies home with them to administer DMSO for Down syndrome at home.

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DMSO Stand-Alone Therapy: Oregon Research

In 1975, another study was done by Dr. Stanley Jacob and a group of other researchers on the use of DMSO for Down syndrome as a stand-alone treatment. This study involved the use of DMSO as an orally administered medicine. The researchers in this study looked at the use of DMSO on patients with developmental delays which included some patients with Down syndrome, but the study did not talk about which patients or how many of the patients had Down syndrome. Though the testers in the study were blinded, like the Chilean research, it was not a double-blind study. The lack of a detailed description of study participants and the inability to use a double-blind approach once again, caused the scientific establishment to dismiss the study.

In this study, 34 children with developmental delays were given a high dose of DMSO. A different group of 33 children with developmental delays were given a low dose of DMSO. Yet another group of 22 children with developmental delays were given no DMSO treatment at all.

Nonetheless, this study gives Lydian and I pause because, though there were no significant side effects reportedly caused by DMSO, the no-dose group of participants actually had the greatest gains in terms of language skills. This is important in light of certain other studies that have been published showing that DMSO may cause apoptosis of nerve cells in young children. 

It also deserves mention that in other studies involving DMSO and amino acids, language skills improved significantly. These are believable results, but at the same time, yet other studies into DMSO administration and neuronal apoptosis in rats shows that nerve cell damage occurs at 0.3 mL per kilogram of body weight at a concentration of 0.5 to 1%. One study cites the fact that many children who undergo bone marrow transplants are exposed to DMSO at a much higher dose than 0.3 mL/kg body weight and thus may experience nerve cell damage. 

Lydian and I know from our experience researching cures for many different diseases that often, research studies are contrived by Big Pharma to throw the general public off the scent of cures. Fear tactics are used to ensure that people stop looking at medicinal agents like DMSO because DMSO works so well to cure disease. 

So while many parents who read the results of the studies I describe above might have a knee-jerk reflex to simply avoid DMSO use in children, there are many studies also showing that DMSO can repair DNA structure. This fact has led to the successful use of DMSO as a cure for cancer, for example. DMSO has been combined with various medications, including chemotherapy in very tiny doses, to cure cancer in conventional medicine and these treatments can and often are used successfully in children with no harmful lasting results. DMSO is often combined with chlorine dioxide solution, Lugol’s iodine, or frankincense essential oil to treat cancer in children too and its use in this context can, without a doubt, save a child’s life. DMSO, even at relatively low concentrations prevents the growth of cancer and causes the death of cancer cells or it causes cancer cells to return to a normal state of health.

Click here to buy Lugol's iodine 2%. 

Note that one of the most important nutrients for nervous system health and the intellectual development of children is Lugol's iodine (which contains two forms of iodine). Click here to learn more about how iodine deficiency impacts the nervous system. Click here to learn about the safety of frankincense essential oil in babies and children.

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So, as a parent or guardian of someone with Down syndrome, the use of DMSO should be carefully considered. Let’s say, for example, that I have a child with severe developmental delays or Down syndrome. I know that some studies have shown that DMSO can improve certain symptoms of Down syndrome. I know that studies also show that sometimes DMSO worsens language skills or causes nerve cell death in animals like rats. I also know that yet other studies show that Down syndrome children who have been treated with DMSO may do worse in terms of language skills during a period immediately following treatment with DMSO. What should I do? 

This is a question only a parent or guardian can answer based on their situation. As I consider the research that’s currently available on Down syndrome, I immediately become curious about whether or not language skills in the untreated DMSO group might improve at a later time in children treated with DMSO. There are no studies showing whether “pruning” might be at work here in the baby rats that were studied, for example, as a neurological phenomenon that happens in human children. “Synaptic Pruning” is a neurological term that’s used to describe a phase in the development of the human nervous system when synaptic connections are eliminated in favor of the development of making other synaptic connections. The process of getting rid of certain synaptic connections happens naturally in humans and other mammals as part of neural “plasticity”. Synaptic pruning occurs from infancy through the late-20s and possibly beyond. Essentially, I would be curious about whether or not language was deprioritized by the brains of the baby rats who received DMSO treatment in favor of developing other areas of the brain. Pruning, after all, is influenced by the environment and it is regarded as an integral part of learning. Depending on the patient’s situation, it might make sense for me to try DMSO at the risk of deprioritizing language development in favor of improving other health-related parameters.

Also, I would want to note that DMSO studies in rats and other animals have yielded results that could not be replicated on humans. For example, temporary and non-harmful changes in the lens of the eye can happen in animals given DMSO, but these same changes have never been observed in humans. So this fact is also worth considering if you have a child with a learning disability or Down syndrome.

Studies into cellular apoptosis (programmed cell death) in adult humans have shown that DMSO works in tandem with caspase-9, an enzyme that initiates caspase, which is a vital part of the apoptotic (programmed cell death) pathway found in many human tissues. The interaction between DMSO and caspase-9 has been used to explain to some extent why DMSO is such a valuable tool in curing cancer. Normally caspase-9 is distributed in the cytosol of healthy cells, but when this enzyme moves into the nucleus of a cell, which happens when a cell is under some kind of stress, the cell is in a pre-apoptotic state known as the Pre-apoptotic Cell Stress Response.

DMSO can’t prevent the movement of caspase-9 into the nucleus of a cell, but it can, under certain circumstances, trigger the redistribution of caspase-9 out of the nucleus back into the cytosol of the cell depending on the timing of exposure to DMSO. This is a temporary migration of caspase-9 back into the cytosol which essentially promotes the overall health and extends the lifespan of cells including brain and nerve cells.

Click here to read more about DMSO Potentiation Therapy (DPT) to cure cancer.

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Research and Anecdotal Reports of Success Using DMSO for Down Syndrome and Learning Disability

Jacob

One family described and posted their experiences using DMSO for Down syndrome online. According to this web site, DMSO can be extremely valuable as a tool to ensure that nutrients are delivered to cells. The family noted that “Jacob”, a 2.5 year old boy with Down syndrome was given Targeted Nutrient Intervention (TNI) for Down syndrome along with DMSO. They administered the DMSO in food, which is something I wouldn’t recommend (because DMSO can combine with substances in unpredictable ways), but nonetheless reported that Jacob’s immediate reaction to the DMSO was positive. He stopped mouthing things and became more happy and active after being dosed with DMSO. He also started gripping his mother’s hand instead of his hand being loose in her grip when she held it. Unfortunately, however, the body odor caused by DMSO was hard for the family to tolerate. 

In regard to the body odor caused by DMSO: if you administer a tiny dose of DMSO to people in the house with the person being treated with DMSO, it makes it so that the untreated people can’t smell the treated person. Finding the right dose of DMSO to make the smell of someone being treated with DMSO more tolerable involves trial and error. Also note that anyone else in the household who takes DMSO should check with a doctor if they are also taking other prescription medications at the same time.

This family reported that TNI vitamins for Down syndrome along with piracetam therapy did not produce immediate results, but DMSO did. They stopped using the DMSO because of the body odor, but later, at age 5.5 years they tried using DMSO again for one day of the week, administering a ⅓ dose 3 times daily. They were no longer working with the TNI for Down syndrome at that time and the mother in this family was likely unaware of studies regarding the ketotic hypoglycemia that is common in Down’s syndrome because she was giving Jacob large amounts of sugar in the morning to cover up the taste of the DMSO. Low blood sugar with high ketone levels (ketotic hypoglycemia) can cause brain fog and behavioral issues in children with Down’s syndrome which was likely why the mother felt compelled to give her son higher than normal doses of refined sugars with his breakfast (to raise his blood sugar levels so that the son’s brain fog would lift temporarily). Using refined sugars to raise blood sugar levels later would result in a sugar crash and worsening behaviors. She reported that without the enriched nutrient therapy, and giving her son large amounts of sugar with the DMSO on one day of the week produced no noticeable results in terms of reducing the symptoms of Down’s syndrome. This isn’t surprising.

The dose that she gave her son at age 2 was 1 mL of DMSO per day as an oral dose. She divided the 1 mL into 5 separate oral doses. At age 5 years, she gave her son 2.5 mL per day in 3 divided doses.

Yris Lara’s Therapy Center

The Yris Lara Therapy Center in located in Santo Domingo, Dominican Republic. It takes about 2 hours to fly to the center from Miami, Florida. This center uses treatments that follow research done in Santiago, Chile and Buenos Aires, Argentina to reduce symptoms of Down Syndrome. Dr. Nicholas Weinstein was the one who pioneered the amino acid-DMSO therapy being used at the center. Therapy seeks to improve the following using DMSO and amino acid therapy:

• Dynamic coordination
• Hand-eye coordination
• Language
• Body control
• Posture control
• Dexterity
• Speed
• Spatial reasoning
• Temporal reasoning
• Physical characteristics (if therapy is done before age 6)

To make an appointment at the Yris Lara Therapy Center, send an email to: [email protected] or contact the Calvo Mackenna Children’s Hospital in Santiago, Chile for information about DMSO for Down syndrome. 

Weinstein Therapy at the Yris Lara Therapy Center: Alternative Treatment for Down Syndrome, Developmental Delay, and Cerebral Palsy

Dr. Nicholas Weinstein was a German pediatrician who fled to Chile during Hitler’s regime. The Chilean government was very interested in Dr. Weinstein’s Down Syndrome therapy and he eventually became famous throughout South America for the successful treatment of Down syndrome children. Doctors from all over the world go to South America to learn how to reduce symptoms of Down syndrome using DMSO and amino acids.

Dr. Weinstein’s medicine is known as AKRON and/or MERINEX (depending on the country where it is administered). 

Weinstein Therapy for Down Syndrome: Treatment Overview

Treatment involves forty outpatient intramuscular injections of DMSO and amino acids given every other day followed by a 30 day rest period. The first five days of treatment at the center are done in-person under the supervision of medical staff. After that, the DMSO-amino acid injections can be given at home.  The staff also administer Secretin, a hormone that regulates water balance throughout the body. Secretin is produced naturally in the human body. It is given to reduce edema and inflammation.

The DMSO helps the amino acids penetrate the blood-brain barrier to promote optimal neural function which is suppressed in those with Down syndrome and developmental delays. For best results, this therapy should be administered as early in the child’s life as possible.

Medical supervision by staff and treatments including a 1-year supply of injections and oral medications is $5,500 USD at the time of this writing (2024). Staff at the treatment center meet patients who are flying into the Dominican Republic at the Las Americas Airport to drive them to their hotel. Treatment begins the following day.

The initial 5-day outpatient treatment includes meals. 

There are no major side effects of adverse effects caused by the DMSO-amino acid treatments.

Research Study #1

One study involved an experimental group of 18 children with Down syndrome and a control group of 91 children of similar physical and mental ages. This study was led by Dr. Lydia F. de Corint, Assistant Head of the Neurological Service of the Municipal Pediatric Hospital in Buenos Aires, Argentina. Each child’s behavior and IQ was measured before and during the study. The Gesell test for child development was used to measure developmental age in babies while the Therman-Merril test was used for older children in both the control group and the experimental group.

Children were observed for 6 consecutive months. Only 18 children received the DMSO-amino acid therapy for Down syndrome. Treatment involved 5 intramuscular injections of 12 ampoules of the DMSO-amino acid compound every other day. Amino acids were administered orally as needed, the children’s diets were healthy, and psychopharmacological treatments were occasionally administered, if needed.

Children in the control group received only basic treatment without the DMSO-amino acid therapy. 

Children in the experimental group received daily oral supplementation with 1-3 capsules containing DMSO for 180 days.

Results from this study showed that the children treated with DMSO and amino acids showed marked progress in terms of language. Side effects were minimal, however one child did have to have treatment suspended due to a probable allergic exanthema (skin rash).

Research Study #2: DMSO for Down Syndrome and Developmental Delays

This study was led by Dr. Manuel Aspillaga, Associate Professor of Pediatrics and Director of the Department of Genetics at the University of Chile. 

In this study 55 children with Down syndrome and different types of developmental delays were divided into an experimental and a control group. The control group contained 24 children while the experimental group was made up of 31 patients who received the DMSO treatment for Down syndrome. Specialists including pediatricians, a psychologist, an ophthalmologist, and a neurologist conducted exams on the children before the study began and then every 6 months thereafter. Pediatricians conducted exams monthly.

Children ranged in age from infancy to age 14 years. In children over 3 ½ years of age, the DMSO-amino acid therapy was administered via intramuscular injections according to a different schedule. Children under 3 ½ years of age were given injections every other day for 90 days with 30 days of rest during which time no injections were given. The cycle of 90 days of treatment followed by 30 days of rest was administered for at least 3 cycles. Dosage was adjusted to each patient’s body weight.

Children over 3 ½ years of age received cycles of 5 cc intramuscular injections of DMSO and amino acids daily for 20 days with a rest period of 20 days. These children were also given amino acid capsules daily but without DMSO as an ingredient in the capsule. Each child went through 5 cycles of 20 injections over the course of 20 days for a grand total of 100 injections of 5 cc treatments over the course of 30 weeks.

Children who were under 3 ½ years of age were compared to the control group to determine the following results:

• Untreated children began the study with an average MOTOR INDEX SCORE of 56. After one year of treatment, the motor index score rose to 58. 
• In comparison, all except for 6 of the treated children began with an average motor index score of 56, but their motor index score rose to 72 over the course of one year of treatment. Six treated children made no progress in terms of their motor index scores.

• In terms of ADAPTATION, the children in the control group had a score of 52 at the beginning of the study and a score of 49 at the end of the study. 
• In the treated group, children began with an average score of 50 at the beginning of the study and a score of 66 after the DMSO-amino acid treatments.

• In terms of LANGUAGE, children in the untreated control group had an average score of 56 at the beginning of the study and a score of 54 at the end of the study. 
• The group of treated patients, in contrast, had a language score averaging 52 at the beginning of the study and 58 at the end of the study. Four of the children improved by more than 10 points from beginning to end.

• In terms of SOCIALIZATION, children in the untreated control group had an initial score of 45. This score rose to an average of about 50 after 1 year.
• The treated children in the experimental group, in contrast, had a social average of 40 at the beginning of the study and 64 at the end of the study. Children in the treated group were generally able to express themselves more clearly by the end of treatment. 

• The author of this study did not note whether physical changes occurred in children under 3 ½ years. 

In children who were older than 3 ½ years, the following results were observed:

• The control group made no progress in terms of MOTOR SKILLS. Their average initial score was 34 at the beginning of the study and 36 at one year later.
• In the treated group, motor skills averaged 38 at the beginning of the study and 49 by the end of the study. 

• In terms of LANGUAGE, the untreated control group made no progress over the course of 1 year.
• Children in the DMSO-amino acid treatment group, in contrast, showed a 16 point increase on the average in terms of language expression and comprehension.

• In terms of PHYSICAL APPEARANCE, the control group did not change in any noticeable way.
• In the treated group, their initial age average of 24 points increased to 39 points during treatment.

The five doctors who worked on this study noted that the DMSO-amino acid therapy in children with Down syndrome and developmental delays. Children under the age of 3 ½ years benefited the most due to therapy in terms of becoming more receptive to stimulation and showing more interest in their environment. Children in this age group also see an increase in muscle tone and physical activity. Their adaptability to new situations and their ability to successfully socialize with others also improved notably with DMSO-amino acid therapy.

The researchers in this study later reported that they treated patients with higher doses which led to better results. 

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DMSO-Amino Acid Formula for Down Syndrome

The DMSO-amino acid formula that is used at the Yris Lara Therapy center is sold under the name “AKRON” in Argentina or “MERINEX” in Chile. The amino acids contained in these formulations specifically act to keep nervous system cells in a constant supply of precursor nutrients that are needed for healthy neurotransmitter production. 

AKRON and MERINEX have been used to treat all of the following:

• Major depression
• Anxiety
• Psychic disorders related to menopause
• Geriatric fatigue and apathy
• Learning disability in children
• Poor intellectual performance in children

The amino acids found in AKRON / MERINEX include:

• Gamma-aminobutyric acid (GABA)
• Gamma-amino-betahydroxybutyric acid (GABOB)
• Acetylglutamine

During each intramuscular injection, 5 mL ampoules are administered. AKRON / MERINEX capsules are given for administration by mouth.

The Weinstein Method at the Yris Lara Therapy Center for Learning Disabilities

About 85% of children with learning disabilities benefit from the DMSO-amino acid therapy developed by Dr. Weinstein. Though learning disabilities are typically regarded as an educational issue that can’t be resolved using nutrients or any kind of medication, in fact, researchers have found that DMSO-amino acid therapy works to improve intelligence. Indeed, Dr. Turkel also found that administration of vitamins and minerals helped learning disabled patients make significant improvements in their intellectual functioning.

At the Yris Lara Therapy Center, amino acids, inorganic phosphates, and potassium are sometimes administered with DMSO to improve brain cell function. Doctors have found that the administration of certain nutrients in combination with DMSO activates the brain to allow patients to overcome learning disabilities.

DMSO for Learning Disability: Research Study #1

One study conducted in 1969 at the Department of Abandoned Children of the National Health Service of Chile was led by Dr. Carlos Nassar on 44 school-aged children with learning disabilities and developmental delays. Dr. Nassar administered MERINEX (DMSO and amino acids) via injection and by mouth.

The learning disabled and developmentally delayed children manifested a variety of behaviors and challenges including:

• Difficulty learning to walk
• Difficulty learning to speak
• Psychomotor delays
• Aggressiveness
• Irritability
• Seizures
• IQ between 30-85

The study participants were given IQ tests at 3, 6, and 10  months after beginning DMSO-amino acid therapy. Dr. Nassar administered 20 intramuscular DMSO-amino acid injections along with oral administration of DMSO capsules. All children received treatment from 6-10 months. Six children received an extended treatment that lasted for 1 year.

Dr. Nassar reported that, in contrast to all other methods used to treat these children, the DMSO-amino acid therapy caused extraordinary gains in terms of intellectual capacity. About 70% of the treated children had a favorable response to treatment in regard to the following:

• Increase in IQ
• Overall improvement in intellectual ability
• Progress in reading, writing, and mathematics
• Better physical coordination
• Improved hand-eye coordination and dexterity
• Decrease in behavioral problems
• Improved psychomotor control
• Reduction in angry outbursts
• Reduction in irritability

DMSO for Learning Disability: Research Study #1

Another study led by Dr. Azael Paz at the Department of Psychiatry at the University of Chile worked with 50 learning disabled children that specifically had only a language disorder between the ages of 5 and 15 years of age. These children did not have an organic brain disease, congenital brain damage, epilepsy, or any kind of developmental delay. They merely suffered from some type of language disorder.

In the study, 30 patients were given MERINEX (DMSO-amino acid therapy) by mouth at a dose of 2-3 capsules daily for 6 months. The remaining 20 children were given DMSO-amino acid injections intramuscularly at a dose three 5 cc ampoules per week up to 20 injections, with a 15 day period of rest between 20 injections. These cycles of injections followed by a rest period continued for approximately 6 months. During the 15 day rest periods, children were given daily doses of 2-3 capsules of MERINEX with the dose depending on the age of the child.

Below is a summary of the results from this study regarding DMSO for learning disability:

• Treated children experienced an increase in energy and the disappearance of mental lethargy.
• Treated children got rid of automatic and repetitive movements.
• Treated children became active instead of passive and more positive instead of having persistent, negative thoughts.
• Treated children became more interested in learning and participating in tasks and activities.
• Treated children began to use facial expressions to communicate more effectively.
• Treated children developed more fluent spoken language.
• Treated children were more social and manifested less unprovoked aggression.
• Treated children engaged in lucid activities.
• Treated children lost their shyness and began to develop a higher self-esteem.
• Treated children became more amenable to doing chores, shopping, eating, and dressing without assistance.
• Treated children were better able to read, write, learn, and do homework.

Doctors who worked with learning disabled children and DMSO-amino acid therapy concluded that this treatment made children capable of school learning. 

Researchers noted that the DMSO-amino acid therapy had a faster effect and was more effective overall in patients who received both injections and capsules in comparison with patients who received only the capsules.

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Summary

DMSO may or may not be helpful as a stand-alone medicine for Down syndrome or learning disability, however, doctors have had success at reducing symptoms of both Down’s and learning disability at therapy centers in Chile, Argentina, and the Dominican Republic using DMSO with amino acids. Indeed, many people today administer vitamin B12 or vitamin C with DMSO to increase the cell’s ability to absorb and use these nutrients. The use of DMSO with certain vitamins, minerals, and amino acids can enhance the healing effects that these nutrients have on the body with sometimes miraculous results.

Based on our own knowledge of orthomolecular medicine and DMSO, it seems that children with Down syndrome and learning disabilities could benefit significantly from administration of nutrient supplements along with DMSO and amino acid treatments. Though DMSO is not technically cure for Down syndrome or learning disabilities, it is as close to a cure as we have been able to find in the scientific and anecdotal literature up to this point. 

Parents of Down syndrome children or learning disabled children might consider the administration of high concentration molecular hydrogen water (also known as Kangen water) to promote healthy DNA, prevent amyloid production in the brain, and to reduce oxidative stress and inflammation. Though there are no studies to date on the use of high concentration molecular hydrogen water for Down syndrome, there are many studies demonstrating that high-concentration molecular hydrogen water is non-toxic and causes no side effects of any  kind. It tastes that water with lower levels molecular hydrogen, but it has the ability to slowly repair certain types of DNA damage. High concentration molecular hydrogen water can be used safely with Targeted Nutrition Intervention, Dr. Turkel’s nutrient therapy for Down syndrome, and DMSO with amino acids. It can even be administered as a nasal therapy. 

Finally, once again, though studies don’t exist yet talking about the use of precursor supplements like Nicotinamide Mononucleotide (NMN), Nicotinamide Riboside (NR) or Nicotinamide Adenine Diphosphate (NAD+) nasal sprays or injections to improve nervous system cell function in Down syndrome, NAD+ and related supplements are worth considering as a treatment along with Dr. Turkel’s orthomolecular medicine, DMSO and amino acids, and high concentration molecular hydrogen water for Down syndrome. 

Click here to schedule a health coaching session with Jennifer and Lydian to learn more about reducing symptoms of Down syndrome at home.

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