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The Carnivore Diet for Chronic Infection

Posted By Jennifer Shipp | Jul 30, 2026

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Heat, Cold, and the Carnivore Diet for Iron Sequestration Due to Chronic Infection

A number of our clients have had success using the carnivore diet in combination with infrared sauna treatments and high heat to keep iron sequestration at bay. When the body is exposed to the cold, the liver responds by acting as a metabolic hub that shifts increased energy production to thermogenesis / heat production. This leads to rapid glycogen depletion. 

Chronic cold exposure leads to an increase in glucose utilization, fatty acid degradation, and the release of fibroblast growth factor 21. This leads to an increase in oxidative stress, inflammation in the body, and potential tissue damage. But that being said, calibrated cold exposure is a potential therapy for diabetes that increases brown fat tissue activity. 

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In other words, a person can use heat exposure and cold exposure to alter how the body uses different resources like glucose. A person can also make a diet change to mostly meats and eggs in order to prevent iron sequestration in the body. Indeed, during some childhood illnesses like diphtheria, doctors would prescribe dietary red meats in high quantities to children early in the progression of the illness with success in preventing some of the most serious symptoms of the disease.

Heat exposure can reduce iron sequestration in the body, acting in some ways like an artificial fever. Cold exposure in limited bouts, in contrast, can promote the release of fat-soluble vitamins from white fat cells which, in turn, can help prevent the body from sequestering these nutrients. When the fat-soluble vitamins become scarce due to sequestration, skin rashes appear and the most serious forms of measles and other types of skin rash can become an issue.

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Resources:
Shen, H. et al. (2019). Brown fat activation mitigates alcohol-induced liver steatosis and injury in mice. Retrieved February 19, 2026 from https://pubmed.ncbi.nlm.nih.gov/30888335/ 1 3

Beijer, E. et al. (2012). A role of active brown adipose tissue in cancer cachexia? Retrieved February 19, 2026 from https://pmc.ncbi.nlm.nih.gov/articles/PMC4419634/ 

Yuko, O. O. and Saito, M. (2021). Brown Fat as a Regulator of Systemic Metabolism beyond Thermogenesis. Retrieved February 17, 2026 from https://pubmed.ncbi.nlm.nih.gov/34176254/

Tabei, S. et al. (2024). Metabolic Effects of Brown Adipose Tissue Activity Due to Cold Exposure in Humans: A Systematic Review and Meta-Analysis of RCTs and Non-RCTs. Retrieved February 18, 2026 from https://www.mdpi.com/2227-9059/12/3/537 

Sarlon, J. et al (2023). Potential links between brown adipose tissue, circadian dysregulation, and suicide risk. Retrieved February 18, 2026 from https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1196029/full 

Vosselman, M. J. et al. (2012). Systemic beta-Adrenergic Stimulation of Thermogenesis is Not Accompanied by Brown Adipose Tissue Activity in Humans. Retrieved February 18, 2026 from https://pmc.ncbi.nlm.nih.gov/articles/PMC3501890/ 

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