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Herbal Remedy for Cancer Pain: Mitragyna speciosa

Posted By Jennifer Shipp | Jun 12, 2026

DISCLAIMER: CONSULT WITH A DOCTOR BEFORE DECIDING ON A TREATMENT PLAN FOR ANY DISEASE.

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Kratom: Treat Cancer and Reduce Pain Using the Same Herb

Though kratom is most famous for its ability to treat cancer-related pain, it can also be administered as an anticancer herb that can shrink tumors and restore health overall. Scientific studies have shown that this herb has a powerful impact on a variety of different types of cancer. It can also be used for cancer prevention. 

Doctors may recommend that patients work with kratom instead of using synthetic opioids to relieve pain. Indeed, kratom can enhance the effects of chemo if the two are used together. We don’t recommend that patients receive chemotherapy, but for patients who feel like chemo is the right medicine for them, kratom can be a useful adjunct treatment.

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There are several proposed mechanisms of action through which is works including:
  • Induction of apoptosis
  • Cell cycle arrest
  • Antiparasitic activity
    • Parasites have been implicated as either an underlying cause of cancer or as a type of infection that is often misdiagnosed and mistaken as cancer. This might explain why ivermectin is successful at treating cancer sometimes. Ivermectin is an antiparasitic that works as a nicotinic agonist. Kratom is also an antiparasitic that works as a nicotinic agonist in the body.
  • Iron metabolism
    • Kratom is a powerful antioxidant that changes ferric iron (Fe3+) to ferrous iron (Fe2+) in the body such that iron can be absorbed. This is similar to what vitamin C does in regard to iron. 
  • Pain relief
    • By relieving pain, patients experience a renewed desire to stay alive.

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Kratom can be used as part of a natural healing protocol for cancer for patients who choose to not work with chemo, radiation, or surgery, but this plant medicine also synergizes with chemotherapy to boost the effectiveness of chemo while reducing pain. In cancer patients, kratom has similar pain-relieving effects as synthetic opioids and cannabis in terms of pain, but like Rick Simpson Oil, kratom is also a powerful anticancer medicine.

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Resources:
Permatasari, H. K. et al. (2025). Kratom (Mitragyna speciosa) in cancer chemoprevention - A provocative functional food perspective. Retrieved May 25, 2026 from https://www.sciencedirect.com/science/article/pii/S2666154325008968


Domnic, G. et al. (2020). Combinations of Indole based alkaloids from Mitrragyna speciosa (Kratom) and cisplatin inhibit cell proliferation and migration of Nasopharyngeal carcinoma cell lines. Retrieved May 25, 2026 from https://www.biorxiv.org/content/10.1101/2020.12.18.423377v2.full


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