Pueraria mirifica belongs to the Leguminosae family of plants which have a great deal to offer both men and women in terms of sexual health, libido, fertility, and general health. These "pea" plants can work various miracles from helping people quit an addiction easily to improving digestive health through improved peristalsis in the intestines.Pueraria mirifica: PCOS Weight Loss Herb to Boost Fertility
Pueraria mirifica, also known as Kwao Krua, is an herbal remedy for women’s health issues. It belongs to the family Leguminosae / Fabaceae along with the soy bean, Trifolium pratense, and Mucuna pruriens, all valuable herbs that can be used to treat infertility in men as well as in women. This family of herbs contains some of the most powerful and least toxic estrogenic herbs that, in some cases, also promote the release of testosterone. Pueraria mirifica has long been used to treat a wide range of different health issues, particularly those pertaining to the aging process, but research also points to its utility as an herbal remedy for infertility.Though the soy bean contains isoflavones that help many women through the initial stages of menopause, but unfortunately, genetically modified soybeans that have been sprayed with toxins like organophosphates may cause more health problems than they resolve. So, in this discussion, we’ve chosen to focus on the Pueraria mirifica, Mucuna pruriens, and Trifolium pratense members of the Leguminosae / Fabaceae family.
All of these herbs must be studied carefully in order to find truthful, honest information about them because they all have powerful healing effects on the body that make it possible for people to overcome serious health challenges from addiction and mental health issues to parasites, cancer, dementia, and any disease process that involves overgrowth of tissues (endometriosis or fibroids, for example) or degeneration of the body (autoimmune disease, for example). The members of this bean-family contain nutrient medicines like L-Dopa (as differentiated from prescription L-Dopa which differs in terms of molecular shape as well as content in that prescription L-Dopa also contains carbidopa, which is toxic to brain tissues) and Vitamin B17 / Amygdalin. Mucuna pruriens has been known to reverse the aging process in notable ways such as re-pigmenting gray hair in elderly individuals. So, you can imagine that these herbs are a big threat to Big Pharma. Thus, it isn’t hard to understand why the scientific literature covering the miraculous medicinal utility of these herbs might be hard for the average person to find.
Strategically, Big Pharma labeled the famous prescription Parkinson’s drug “L-Dopa” after a nutrient with the same name in an effort to confuse the public and cast fear over the amazing little velvet bean plant that can be eaten in soups along with fava beans and other bean and pea plants in the same family that contain similar medicinal agents in various configurations. The public has been programmed to remember the so-called “Levodopa / L-Dopa” prescription drug as a scary medicine that wears off over time, leaving Parkinson’s patients at the brink of death with no possible treatment to bring them back to life. But the real, nutrient Levodopa / L-Dopa is very safe, in fact, and it heals the brain rather than damaging the brain and body.
Vitamin B17/ Amygdalin is another substance found in bigger and smaller quantities in this family of plants. Trifolium pratense contains the highest quantity of this incredible substance which has literally been made illegal in the U.S. because of its ability to cure 80-90% of all cancers even as a stand-alone treatment. Trifolium pratense, also known as red clover, is a vital ingredient in the herbal cure for cancer known as The Hoxsey Tonic, but this “noxious weed” that grows in practically every American lawn is also a powerful, natural fertility treatment. It is especially valuable in the treatment of issues regarding endometriosis or fibroids, which are benign cancer-like diseases involving proliferation of tissues.
Pueraria mirifica, of course, is another miracle herb which means that Big Pharma works hard to cover up its usefulness and a substantial amount of funding is likely diverted into making sure the public, especially women, never learn about the true value of this herb.
Writers like me compete with Big Pharma for airtime online and it’s gotten harder and harder for patients to find real, honest information about natural treatments for sexual health like Pueraria mirifica. And Pueraria mifirica is an herbal contraceptive for women, which means that it is shunned with even greater force by Big Pharma because women’s sexual health and contraceptive choices are another Big Business. Women who discover the potential of an herbal birth control option like Pueraria mirifica are empowered to live normal, healthy lives, after all, rather than being chained to The Machine by health problems caused by the pill and other contraceptive devices like the IUD.
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Pueraria mirifica Safety
It’s important to note that Pueraria mirifica is a woman’s herb. Men should not take Pueraria mirifica because of its high phytoestrogen content.That being said, in women, Pueraria has an excellent safety profile when women take it at the proper dose (which we discuss later in this article).
Medicinal Effects of Pueraria Mirifica
The tuberous roots of P. mirifica contain 17 compounds with estrogenic activity. These 17 compounds are typically divided into the following three groups:Group 1: Teniso Flavonoids
- Genistin
- Genistein
- Daidzein
- Daidzin
- Kwakhurin
- Kwakhurin Hydrate
- Tuberosin
- Puerarin
- Mirificin
- Puemiricarpene
Group 2: Coumestans
- Coumestrol
- Mirificoumestan
- Mirificoumestan glycol
- Mirificoumestan hydrate
Group 3:
- Miroestrol
- Deoxymiroestrol
- Isomiroestrol
All of the above substances are phytoestrogens and all of them have a structure similar to that of beta-estradiol. But miroestrol is the substance with the most significant estrogenic activity and it is most similar to estriol, which is considered to be the safest estrogen in humans.
Pueraria mirifica is an herb that is famous for its ability to increase breast size in women, but this herb contains powerful phytoestrogens that can also act as a natural herbal contraceptive and an herbal alternative to birth control pills. The pueraria plants tend to normalize blood sugar levels and indeed, Kudzu (another member of the Leguminosae / Fabaceae family) is an herb that is hugely beneficial in overcoming not just sugar addiction but also alcohol addiction via its action on normalizing blood sugar levels. As such, research has shown that the pueraria plants such as Kudzu, can be used to naturally boost weight loss and reduce body mass index. Of special note is Kudzu’s ability to reduce visceral body fat, or the fat surrounding the organs. Pueraria mirifica also promotes weight loss naturally (unlike prescription birth control pills) which, in turn, can benefit women who suffer from PCOS and the fertility problems associated with this disease. When combined with Lugol’s iodine therapy, Pueraria mirifica and the other Leguminosae plants have a lot to offer in terms of women’s sexual health and fertility in particularly.
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Pueraria mirifica as an Herbal Contraceptive
Pueraria mirifica is an herb that originated in Burma and Thailand. In female Macaca fascicularis monkeys, P. mirifica caused a lengthening of the menstrual cycle with total disappearance of menstruation in monkeys that were treated with 1000 mg of Pueraria mirifica daily. The menstrual cycle length increased substantially, however, even in monkeys that were treated with 10 mg and 100 mg of Pueraria mirifica daily.In addition to its estrogenic effects, in this particular study, Pueraria mirifica also lowered:
- Follicle Stimulating Hormone
- Luteinizing Hormone
- Estradiol
- Progesterone, and
- Irinhibin
Higher doses of Pueraria mirifica exerted a more pronounced effect on lowering the above listed hormones in monkeys. Changes in the length of the menstrual cycle and hormone levels in monkeys recovered after treatment with Pueraria mirifica at 10 mg per day and at 100 mg per day, but the monkeys treated with 100 mg per day but monkeys treated with 1000 mg per day apparently did not recover normal menstruation after treatment. Monkeys are smaller than humans, though so this dosing strategy would be different for humans.
Studies on Pueraria mirifica have yielded contradictory results in terms of its function as a natural contraceptive for women. A different study involving both rats with ovaries and rats without ovaries showed the following hormone levels increased significantly during treatment:
- Testosterone
- Follicle Stimulating Hormone
- Luteinizing Hormone
- Prolactin
- Growth Hormone
This study showed that isoflavones in Pueraria mirifica can sometimes increase estrogen levels (as in the rats without ovaries who needed more estrogen) by increasing Gonadotropic-Releasing Hormone. In rats that still had their ovaries, Pueraria mirifica decreased estrogen levels.
This effect on estrogen levels wherein the estrogen levels may be either increased or decreased by Pueraria mirifica depending on the animal’s need can be explained by looking at scientific studies on Pueraria mirifica in post-menopausal applications. While research into the use of Pueraria mirifica for contraception in menstruating women of child-bearing age are contradictory and, dare I say, scary– research into the use of Pueraria mirifica as an herbal remedy for menopause symptoms is fairly well-developed and easy to understand. Studies into Pueraria mirifica for menopause regularly mentions the fact that P. mirifica is a Selective Estrogen Receptor Modulator that selectively binds to estrogen receptors to act as either an agonist that promotes estrogens binding to the receptors or an as antagonist that prevents estrogens from binding to the receptors depending on the needs of the study participant.
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Miroestrol: Natural Estrogen Replacement
Miroestrol is the substance that tends to get the most attention as a singularly important substance in Pueraria mirifica because it is rare to find a plant that contains such high levels of estriol phytoestrogens. Interestingly, though certain studies warn against the use of Pueraria mirifica for contraception because of its apparently carcinogenic effects on the body, in the scientific literature on menopause, miroestrol is said to compete with toxic human estrogesn in the body to block estrogen receptors that are involved in breast cancer and endometrial cancer. Indeed, miroestrol and other phytoestrogens in Pueraria mirifica go to work in menopausal women to support bone density, improve heart health, and yes, also relieve symptoms of menopause.Other studies have backed up these results by showing that Pueraria mirifica stimulates estrogen in animals that need more estrogen and it lowers estrogen levels in animals that have normal or high levels of estrogen, but in studies observing Pueraria mirifica for birth control, the selective estrogen receptor discussion is conspicuously absent. And scientists seem to be mystified by the “contradictory” effects of Pueraria mirifica on a woman’s body.
So why is there a discrepancy between the scientific literature talking about the use of Pueraria mirifica for birth control versus the use of Pueraria mirifica for menopause? It’s hard to say exactly, but through my eyes, it looks like there is a difference in terms of funding or perhaps funding sources. In other words, while studies into herbal treatments for menopause have been funded, studies into herbal contraception have been less well funded and perhaps even politicized wherein scientists are inclined to observe and write about certain results (real or fake) rather than observing the actual data. Scientists, after all, have to put food on the table too, so they often pander to Consensus Based Science in order to get funding. But because I can’t say for sure that this is what’s going on, you should read this article and think carefully about how you choose to apply the information here. And note that generally, the average daily dose of Pueraria mirifica is between 25 to 200 mg/day though some women take up to 800 mg per day. Don’t take higher doses if you’re using P. mirifica as a stand-alone contraceptive if you think you might want to get pregnant later.
Pueraria mirifica: Herbal Remedy for Menopause Symptoms
Despite the inconclusive research regarding Pueraria mirifica as an herbal contraceptive for women, this herb is well known in terms of its ability to relieve post-menopausal symptoms such as hot flashes, low libido, and vaginal tissue thinning. The research into Pueraria mirifica as an herbal remedy for menopausal symptoms is extensive and it generally points to beneficial effects on women’s body when it is taken at the proper dose. Whether you are post-menopausal or young and fertile, it would benefit you to consider taking Lugol’s iodine as a supplement daily to prevent breast cancer and other reproductive organ cancers. Learn more about Lugol’s iodine therapy here.
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In menopause, Pueraria mirifica releases isoflavones that modulate estrogen receptor expression. Studies recommend that menopausal women continuously take Pueraria mirifica at 20-100 mg per day for 6 months or at 100-200 mg per day for 12 months. No adverse effects were noted in women who took this Pueraria mirifica dose.
Indeed, post-menopausal pre-treatment with Pueraria mirifica at 1000 mg/kg body weight per day for 28 days has been shown to prevent breast cancer and breast tumors in animal models of cancer. But, as mentioned previously in this article, high doses of Pueraria mirifica (more than 800 mg per day) in women of child-bearing age may be unwise given the supposed sterilizing effect of high dose Pueraria mirifica in monkeys. Whether sterilization is truly a potential issue or not is still up for debate. It seems unlikely, to be whole truth, but the research is simply not available at this time to prove that Pueraria mirifica is safe in mega doses for young women of child-bearing age.
That being said, a number of women take Pueraria mirifica with birth control pills and this can cause women to skip their periods.
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Pueraria mirifica: Herbal Remedy for Uterine Adhesions
Uterine adhesions may develop as a result of a variety of factors, including due to previous uterine or reproductive organ surgeries, or even as a result of certain health conditions like endometriosis, Asherman’s disease, or pelvic inflammatory disease (PID). Women with uterine adhesions may experience difficulty getting pregnant and staying pregnant because the adhesions can sometimes interfere with embryonic implantation and fetal development.Pueraria mirifica may work as a herbal treatment for uterine adhesions in some women. Multiple studies have indicated that uterine adhesions may benefit from estrogen therapy, and as an herb with estrogenic properties, P. mirifica can help naturally increase estrogen levels. For example, one study indicated that, in rabbits with uterine adhesions, estrogen therapy was able to significantly reduce the presence of uterine adhesions and tissue fibrosis. While synthetic hormone replacement therapy can cause a long list of adverse effects, herbal medicines like P. mirifica tend to be significantly safer and pose less of a risk of side effects.
Lower doses of Pueraria mirifica have been shown to dramatically increase fertility and pregnancy rates; however, higher doses can actually produce the opposite effect, both in terms of general fertility and in terms of the healing of uterine adhesions. A dose of 10mg/kg of bodyweight, though, has been shown to be unlikely to negatively affect the female reproductive organs, and in fact can support the health and healing of these organs at this dose.
We talk about cures for uterine fibroids and adhesions in more detail here.
Pueraria mirifica: Herbal Remedy for Endometriosis and Endo Belly Cure
At the appropriate dosage, Pueraria mirifica may be an effective treatment for endometriosis. Studies have shown that lower doses of this herb can inhibit the proliferation of excess endometrial tissue (note, however, that higher doses can actually encourage endometrial proliferation, so careful attention to dosing is important). A related plant, Pueraria lobata (Kudzu), may also have positive effects in the treatment of endometriosis. One 2017 study indicated that kudzu can help inhibit the adhesion and migration of endometrial cells, in addition to reducing the incidence of endometrial lesions; the same study suggested that Pueraria mirifica may not only cure, but also prevent the development of endometriosis.As we mentioned earlier in this article, Pueraria mirifica is unique in that it can increase or decrease estrogen levels (thereby bringing the reproductive hormones back into balance) based on the individual needs of the patient. Unlike pharmaceutical drugs, plants are wise in this way. Many, many different plants possess this unique balancing activity that’s based entirely on the patient’s individual ecosystem. I mention this because, if you do a quick Google search on endometriosis and estrogen, you’re likely to find a bunch of articles saying that endometriosis patients have high estrogen levels. And then, you might come to the conclusion that a plant like Pueraria mirifica with estrogenic qualities might actually hurt an endometriosis patient… unless you were already are aware that this specific plant can actually work with estrogen directly to lower it in cases where it’s too high (and to increase it when it’s too low).
Pueraria mirifica also has some anticancer actions in the body, and has been shown to potentially prevent/treat certain forms of breast cancer as well as cancer metastases. Since the pathology of endometriosis closely resembles that of cancer, this is an important point, especially since P. mirifica has action against cancers that are hormone-sensitive. Other related Pueraria plants, including P. lobata (kudzu) and P. thunbergiana, also possess some specific anticancer compounds.
Kudzu (Pueraria lobata), a related plant, has been shown to help support healthy digestion, and can relieve an upset stomach and improve bowel movements. It has a gelatinous, bulking consistency that lends itself well to producing firmer, easier-to-pass bowel movements, and which also can help coat the digestive tract and ease the symptoms of leaky gut syndrome, IBS, and diverticulitis. Kudzu as well as Pueraria mirifica may therefore help remedy some of the symptoms of endometriosis, including Endo Belly.
In this 2017 study, female mice were given a dose of 150-300mg/kg of body weight for 5 weeks in the form of Pueraria lobata flower extract. However, other studies have indicated that doses this high over a longer period of time may prove more detrimental than valuable, and that a dose of 10mg/kg is more likely to support female reproductive organ health and healing.
Read more about cures for endometriosis at this link.
Miroestrol for Women’s Health
Pueraria mirifica contains the phytoestrogen known as miroestrol, which acts as a selective estrogen receptor modulator that binds competitively to estrogen receptors in the body, thus blocking excessive estrogen receptor stimulation by other, possibly more toxic forms of estrogen. The root extract of Pueraria mirifica has no known side effects and there are no known drug interactions reported for this herb.As a natural treatment for menopause, Pueraria mirifica has been studied in terms of its ability to do all of the following:
- Reduce bone loss after menopause
- Reduce hot flashes
- Improve blood lipid profiles
- Protect against cardiovascular disease
- Improve genitourinary function
Studies have shown that Pueraria mirifica is an excellent herbal alternative to hormone replacement therapy after menopause.
Pueraria mirifica, as such, can be used as an herbal contraceptive in women. It has been shown to suppress ovulation in animal models of fertility by lowering serum levels of gonadotropins. If you wish to get pregnant in the future, Pueraria mirifica should be used at the recommended dosage (below 800 mg per day).
Do not take Pueraria mirifica if you are taking prescription estrogen, birth control pills, or if you are pregnant or nursing. Though some women take Pueraria mirifica with birth control pills to stop having periods, the long-term health effects of doing this aren’t established in the scientific literature. Note that reproductive hormones play a role in general health, not just reproduction or reproductive organ health, so exercise caution if you use Pueraria mirifica as a young woman of child-bearning age to stop your periods while also taking birth control pills.
Pueraria root extract is typically recommended in the treatment of menopause-related hot flashes, at a dose range of 200-1000 mg containing 150 mcg Miroestrol. Take up to 500 mg twice per day. Symptom resolution of hot flashes often occurs within a few weeks of therapy.
Pueraria root extract has no known side effects at commonly prescribed doses. There are no confirmed drug interactions found in any clinical trial or quantitative systematic review.
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Resources:
• Trisomboon, H. et al. (2005). Ovulation Block by Pueraria mirifica: A Study of Its Endocrinological Effect in Female Monkeys. Retrieved October 7, 2022 from https://www.researchgate.net/publication/7929795_Ovulation_Block_by_Pueraria_mirifica_A_Study_of_Its_Endocrinological_Effect_in_Female_Monkeys
• Qi, B. L. and Qi, B. M. (2002). Effect of the purariae-isofiavones on estrogen level in normal and ovariectomized rats. Retrieved October 7, 2022 from https://pubmed.ncbi.nlm.nih.gov/12776591/
• Zheng, G. et al. (2002). Estrogen-like effects of puerarin and total isoflavones form Pueraria lobata. Retrieved October 7, 2022 from https://pubmed.ncbi.nlm.nih.gov/12599693/
• Kakehashi, A. et al. (2016). Pueraria mirifica Exerts Estrogenic Effect in the Mammary Gland and Uterus and Promotes Mammary Carcinogenesis in Donryu Rats. Retrieved October 7, 2022 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127102/
• Stansbury, et al. (2012). Pueraria Mirifica for Menopausal Symptom Relief and Tissue Support. Retrieved October 7, 2022 from https://restorativemedicine.org/journal/pueraria-mirifica-for-menopausal-symptom-relief-and-tissue-support/
• Virojchaiwong, P. et al. (2011). Comparison of Pueraria mirifica 25 and 50 mg for menopausal symptoms. Retrieved October 7, 2022 from https://pubmed.ncbi.nlm.nih.gov/20872225/
• Zheng, G. et al. (2002). Protective effect of total isoflavones from Pueraria lobata on secondary osteoporosis induced by dexamethasone in rats. Retrieved October 7, 2022 from https://pubmed.ncbi.nlm.nih.gov/12451975/
• Kamiya, T. et al. (2012). Consumption of Pueraria flower extract reduces body mass index via a decrease in the visceral fat area in obese humans. Retrieved October 7, 2022 from https://pubmed.ncbi.nlm.nih.gov/22878195/
