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Herbal Remedy for Diabetic Neuropathy: Bitter Apple / Citrullus colocynthis

Posted By Jennifer Shipp | Apr 05, 2023

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Citrullus colocynthis has been studied most in terms of its ability to cure diabetic foot or treat diabetic neuropathy naturally.

Cure Diabetic Foot / Natural Blood Sugar Support Using Citrullus colocynthis

This herb, known as bitter apple or Citrullus colocynthis, is used by traditional healers in many parts of the world to control blood glucose levels and treat diabetic neuropathy naturally. Scientific studies have validated that bitter apple juice does indeed reduce blood sugar levels naturally.

The pulpy flesh and seeds of Citrullus colocynthis is an ethanol extract that can be administered to inhibit alpha-glucosidase and DPPH, which can improve diabetes symptoms naturally. Research suggests that this is an herb that’s comparable to glibenclamide in its ability to treat diabetes, though it is slightly less effective. Citrullus colocynthis reduces blood sugar levels, triglyceride levels, and cholesterol levels, but it has also been studied as an herbal remedy for diabetic neuropathy.

Citrullus colocynthis can be used with the frankincense protocol for diabetic neuropathy

Bitter Apple as a Diabetic Neuropathy Cure

As an herbal diabetic neuropathy treatment, Citrullus colocynthis is able to decrease the number of demyelinated and degenerated nerve fibers in diabetic patients. Dosing of Citrullus colocynthis for diabetic neuropathy is at 100 mg / kg of the patient’s body weight per day, though this herbal remedy is usually administered at higher doses to treat all aspects of diabetes mellitus naturally.

Topical application of the extract of bitter apple / Citrullus colocynthis has also been used as a natural cure for diabetic neuropathy. One study investigatingthe use of topical Citrullus colocynthis extracts as an herbal remedy for diabetic neuropathy involved sixty patients who were allocated to either the topical remedy or a placebo for 3 months. Patients were evaluated both before and after treatment to determine whether their pain scores were lower. This study also looked at electrodiagnostic results, quality of life scores, and adverse events to measure results. In this study, patients in the bitter apple group experienced measurable changes in nerve conduction velocity showing that pain control was not just a subjective result. There were actual improvements in nerve health to substantiate the patient reports of natural pain reduction due to the topical bitter apple treatments.

Citrullus Colocynthis Dosing to Treat Diabetes Naturally

Administer 150-300 mg / kg of the patient’s body weight.   

How to apply topical treatments with this herbal remedy for diabetic neuropathy:

Administer topical oil preparations of bitter apple / Citrullus colocynthis up to 3 times daily for natural diabetic neuropathy pain relief.

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Ostovar, M. et al. (2020). Effects of Citrullus colocynthis L. in a rat model of diabetic neuropathy.  Retrieved March 29, 2023 from https://pubmed.ncbi.nlm.nih.gov/31874814/ 

Heydari, M. et al. (2016). Tropical Citrullus colocynthis (bitter apple) extract oil in painful diabetic neuropathy: A double-blind randomized placebo-controlled clinical trial. Retrieved March 29, 2023 from https://pubmed.ncbi.nlm.nih.gov/25800045/ 

Ghauri, A. O. et al. (2020). In vitro and in vivo anti-diabetic activity of Citrullus colocynthis pulpy flesh with seeds hydro-ethanolic extract. Retrieved March 28, 2023 https://pubmed.ncbi.nlm.nih.gov/31971913/ 

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