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Can schizophrenia be cured? Herbs That Treat Schizophrenia and Other Types of Psychosis

Posted by Jennifer Shipp | Sep 04, 2023


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Herbal Remedies for Psychosis

Acorus calamus is a front-liner for mental illness. This herbal cure for schizophrenia and epilepsy is gentle enough to be used in children and babies.
Schizophrenia is regarded as a devastating illness not just for the patient, but for loved ones and family members as well. Most ant-psychotic drugs unfortunately cause undesirable side effects. Indeed, most antipsychotic medications work as dopamine antagonists. This means that they prevent dopamine from binding to dopamine receptors in the brain and body. Dopamine is the neurotransmitter that allows people to feel pleasure and to be able to observe themselves making both wise and unwise decisions. Without adequate dopamine in the brain, apathy and depression can set in as well as sexual problems and an inability to think clearly or feel awake and alive. No wonder schizophrenic patients don’t want to take their prescription medications…

It’s true that abnormally high dopamine transmission in the brain has been linked to psychosis and schizophrenia, but inhibiting the brain’s ability to use dopamine at the receptor sites may not, in fact, be the most elegant way to treat this disease. If you or a loved one has been diagnosed with psychosis, herbal remedies may be something to consider as an alternative to antipsychotics. 

My personal experience with herbal medicines in the treatment of mental illness and disease is that because herbs work through multiple mechanisms of action all at once, side effects from herbal remedies seem to be less than when working with Big Pharma drugs. Herbs act themselves as natural doctors inside the body, balancing things that have become imbalanced, killing pathogens at the same time, and regulating that which needs to be regulated. So while there are a number of herbal antipsychotics that work through a similar mechanism of action as Big Pharma antipsychotics, these herbs don’t always produce the same kinds of side effects as the drug therapies. 

Below, we’ve listed herbs that have been scientifically studied for verifiable antipsychotic effects. Acorus calamus is at the top of this list because this herb seems to be able to cure neurological diseases and mental illness via its ability to regrow parts of the brain. Also, Acorus calamus can be used to treat children which means that it can be applied in a number of situations involving mental illness. 

Click here to read about anti-addiction herbs and natural treatments.

Acorus calamus

Acorus calamus is a compelling herbal medicine for schizophrenia and other forms of psychosis. Like many of the other antipsychotic herbs we list below, Acorus calamus is also a natural treatment for epilepsy. But Acorus calamus is not just a long-term treatment that you might take to prevent seizures. Rather, it actually acts as a permanent cure for epilepsy in about 70% of cases, probably through an anti-tapeworm action as epilepsy is caused by a tapeworm infection in the brain in about ⅔ of all cases. Though this fact is not acknowledged in the United States and other developed countries where Big Pharma is more powerful than traditional medicine, people in other countries of the world often expect to cure epilepsy naturally using natural medicines like Acorus calamus. Click here to read more about epilepsy as a misdiagnosis and as a curable disease here.

Though it’s likely that this plant has an antiparasitic effect that plays a role in curing epilepsy naturally, there are other medicinal effects that make Acorus calamus particularly interesting. This plant actually regrows areas of the brain, in particular the cerebellum. It enhances intellect, treats depression and general debility via this action. In countries where Acorus calamus is used as a traditional medicine, it is regarded as a cure-all for mental illness. Indeed, studies have even shown that Acorus calamus can be given to young patients to prevent autism from developing when autism is suspected. 

Click here to read more about the use of Acorus calamus to prevent autism. 

Click here to read more about the use of Acorus calamus as a cure for schizophrenia and other mental illnesses here.

In dementia patients, Acorus calamus is administered along with Polygala herb to keep intellect and cognition clear in the elderly. This herb is used to treat confusion and forgetfulness naturally in those who have not yet developed a full-blown case of dementia. Its ability to treat general mental illness is noteworthy especially given its low toxicity and gentleness. 

Acorus calamus is used not just to treat schizophrenia naturally, but also as a natural treatment for depressed psychosis. It has a neuroprotective effect against strokes, but it also protects the brain against neurodegeneration caused by exposure to chemicals or heavy metals. 

Acorus calamus is administered at a dose of 30 to 50 mg per kilogram of the patient’s body weight. It is safe for use in babies and children.

Spondias mombin

Many antipsychotic medications that are prescribed to people with psychosis by doctors work by reducing the amount of dopamine that interacts with dopamine receptors in the brain. Spondias mombin is an herbal antipsychotic that has been studied scientifically for its ability to regulate dopamine activity in the brain.

In one study, Spondias mombin leaves were made into three different types of extracts. The air-dried leaves were put into water, methanol, or ethanol to study which type of extract worked best in animals to reduce symptoms of psychosis naturally. The study looked at the effects that each of these herbal extracts had on both amphetamine-induced seizures as well as apomorphine-induced seizures as well. In the study, residues from the different extract types were dissolved in normal saline and then injected intraperitoneally in the rats.

The methanol and ethanol extracts of Spondias mombin were administered intraperitoneally at 12.5 to 100 mg per kg of the patient’s body weight. The water extract was administered at doses of 50 and 100 mg/per kg of the patient’s body weight. All of the extracts reduced behavioral symptoms of psychosis as well as increasing sleeping time. 

Spondias mombin extracts seem to have antipsychotic effects via the GABAergic system. This herb seems to be a GABA(A) agonist. It does NOT, on the other hand, seem to affect the following receptor types according to studies:

  • Muscarinic
  • Alpha(2)adrenergic
  • Mu-opioid 

Scientists noted that the antipsychotic effects of Spondias mombin could not be reversed using yohimbine, naltrexone, or atropine, however, all of the Spondias mombin extracts blocked the effect of flumazenil. 

All of the extracts successfully blocked picrotoxin-induced convulsions in mice. This seemed to be due to anticonvulsant phenolic compounds in this herbal remedy for schizophrenia and other types of psychosis. In other words, Spondias mombin worked not just to treat psychosis naturally, but also as a natural treatment for epileptic seizures.

Crassocephalum bauchiense

Crassocephalum bauchiense is an herbal remedy for schizophrenia and other types of psychosis. It is also an herbal anti-anxiety medicine. Like other herbs that treat psychosis, Crassocephalum bauchiense is also used to treat epilepsy, dementia, and insomnia. This plant is an important herbal remedy for mental illness that’s used in Cameroon.

In one study, extracts of Crassocephalum bauchiense were studied in rats to evaluate different behavioral symptoms of psychosis and other nervous system disorders such as epilepsy, dementia, and insomnia. The study demonstrated that a water extract (such as an herbal tea) of Crassocephalum bauchiense able to inhibit behavioral indicators of psychosis in a dose-dependent manner. In other words, higher doses of Crassocephalum bauchiense had stronger antipsychotic effects while lower doses had lower antipsychotic effects.

Crassocephalum bauchiense also worked as a powerful herbal remedy for insomnia in addition to its antipsychotic effects. This herb appears to work by increasing GABA levels in the brain while blocking dopamine D-2 receptors. GABA-T levels are impacted in particular.

Studies examining the psychoactive effects of Crassocephalum bauchiense use a dose of 100-200 mg per kilogram of the patient’s body weight. 

Synedrella nodiflora

A water-ethanol extract of Synedrella nodiflora has been studied for its ability to treat epilepsy naturally while also acting as a sedative and as a pain-reducer. But as we’ve noted above in our discussions of other herbal remedies for psychosis, often herbs that prevent seizures also act as natural antipsychotic treatments. Synedrella nodiflora is no exception. Scientists who have studied this herbal remedy for seizures have noted that animals who were given this herb also show a reduction in symptoms of psychosis. One study administered between 100 to 1000 mg per kilogram of the animals body weight to investigate their hypothesis that Synedrella nodiflora (administered by mouth) functioned as an herbal remedy for schizophrenia and other forms of psychosis.

At high doses, Synedrella nodiflora acts as a sedative, but at low to moderate doses, this herb shows acetylcholine-like and serotonin-like activity. Synedrella nodiflora is less powerful than the antipsychotic medicines chlorpromazine and haloperidol, but scientists have shown that the use of Synedrella nodiflora actually potentiates both chlorpromazine and haloperidol. As such, this herbal remedy for schizophrenia works through a different mechanism of action than the other herbs that we’ve discussed here.

Desmodium adscendens

Desmodium adscendens is an herbal remedy for psychosis that’s used in Ghana to treat depressed psychosis, schizophrenia, manic depression, and more. In Ghana, herbalists use an ethanol extract of Desmodium adscendens to treat mental illness naturally.

Scientific studies have examined this herbal treatment for schizophrenia and other forms of psychosis to determine how and why it works. Like Synedrella nodiflora, Desmodium adscendens appears to work through effects on acetylcholine and the serotonin system. The lethal dose of this herb is very high at 3000 mg per kilogram of the patient’s body weight according to animal studies into its use for psychosis.

By itself Desmodium adscendens does not induce catalepsy, but it can enhance catalepsy caused by haloperidol at a dose of 1000 mg per kilogram of the patient’s body weight. As such, scientists have concluded that Desmodium adscendens does not cause motor-related side effects except at high doses.

It’s worth noting here that Desmodium adscendens is also used to treat asthma and chronic bronchitis in Ghana. This suggests that this herb contains certain nutrients or substances that would have a positive impact on the reproductive organs and/or the thyroid gland. 

Click here to read about Lugol’s iodine and molecular hydrogen as cures for asthma and chronic bronchitis.

This herb is also used to treat the following diseases and disorders:

  • Leishmaniasis
  • Immune System Dysfunction or Imbalance / Autoimmunity
  • Smooth muscle spasm
  • Inflammation
  • Ulcers
  • Heart Disease
  • Diabetes
  • Amnesia / Dementia
  • Viral Infection
  • Liver Disease

Albizia zygia

In African traditional medicine, this plant-member of the Leguminosae family is used to treat mental illness naturally. One scientific study looked at a water and ethanol extract of Albizia zygia as a natural treatment for both the positive and negative symptoms of schizophrenia. This study examined the effects of 30-300 mg per kilogram of the patient’s body weight. At this dose, Albizia zygia reduced all behavioral symptoms of schizophrenia without causing catalepsy. Indeed, at a dose of only 30 mg per kilogram body weight, it significantly inhibited haloperidol catalepsy. Scientists concluded that Albizia zygia is an herbal antipsychotic that has the ability to relieve positive, negative, and cognitive symptoms of schizophrenia naturally.

Albizia zygia is used regularly as an herbal remedy for schizophrenia and other mental health problems in Ghana. Indeed, another group of scientists noted that Albizia zygia has antipsychotic effects.. These scientists found that even at high doses (up to 3000 mg per kilogram body weight), animal models of psychosis did not die, though they did experience central nervous system depression. In other words, the lethal dose of Albizia zygia is high which makes this herb rather safe in mental health situations. In this study, Albizia zygia was administered at a dose between 100-1000 mg per kilogram body weight to produce therapeutic antipsychotic effects. It did not produce catalepsy by itself, but it did increase haloperidol-induced catalepsy at a dose of 1000 mg per kilogram body weight. 

Some studies have shown that Albizia zygia has antidepressant effects as well as antipsychotic effects. Indeed, this herb seems to work as a natural treatment for mental illness in part via its anti-inflammatory action and its ability to treat pain. Albizia zygia is also a fever-reducing herb. Studies into its various medicinal effects have suggested that this herb works by interacting with opioid receptors, adenosinergic receptors, and muscarinic cholinergic pathways in the body.

Myricitrin / Medicinal Substance Found in Several Herbs

Myricitrin is a substance that is found in several plant species including:

  • Myrica cerifera / Bayberry
  • Myrica esculenta
  • Nymphaea lotus
  • Nymphaea odorata
  • Chrysobalanus icaco
  • Polyganum aviculare

This substance has been isolated from plants and is being studied scientifically because it has central nervous system activity and the ability to treat psychosis naturally. Scientists, of course, are mostly getting funding to study this medicinal agent as a substance that may be able to be synthetically reproduced in a lab and exploited by Big Pharma to produce an antipsychotic medicine that doctors can prescribe. But patients can gain access to this herbal psychosis remedy now by taking herbs that contain myricitrin.

Myricitrin inhibits both nitric oxide and protein kinase C (PKC). It has an anti-anxiety effect in humans. Nitric oxide inhibition effects caused by myricitrin seems to have a natural antipsychotic effect. And PKC inhibition has also been shown to reduce psychotic symptoms naturally in bipolar patients.

Studies have shown that myricitrin had a natural antipsychotic effect at doses that do not cause catalepsy. Scientists believe this effect may have to do with its action as a nitric oxide inhibitor.


Though conventional medicine regards psychosis as an incurable mental illness, in fact, there are cures for this problem. Indeed, a number of alternative medical models regard psychosis including depressed psychosis, manic psychosis, schizophrenia as an energetic issue. The plants that we’ve listed above likely work to restore the proper flow of chi in the body as part of their medicinal action. Herbal cures for schizophrenia and psychosis can be extremely helpful, but if you’re committed to finding a cure, it might be valuable to seek out someone to do other forms of therapy as well.

As someone with an advanced degree in family psychology, I learned years ago, that families that include psychotic patients often have a somewhat predictable dynamic. This mainstream view of schizophrenia assigns a lot of blame to the family of origin for psychosis (as well as for other types of mental illness), which eventually led me to seek out other ways to view mental illness. I eventually discovered Constellation Therapy as a much less judgmental way of viewing psychosis that can, at least some cases, lead to a cure. 

Reiki, Barbaran Brennan healers, and shamanic medicine practitioners can also sometimes help patients with psychosis. Epilepsy, for example, is viewed in many cultures as a form of soul loss that can be treated by trained shaman. Brennan healers work with “schizoid personality” types who project their energy upward rather than downward which might be viewed as a problem that’s similar to soul loss, if not exactly the same thing. Often, family members who are close to the patient must also seek out treatment using energy healing modalities in order to see a shift in terms of psychosis and mental illness. 

If you’re truly committing to finding a cure for psychosis or another type of mental illness, keep an open mind and look at other systems of medicine. Work with herbs rather than prescribed drugs. Make the diet healthier and ensure that the patient receives plenty of essential amino acids every day. Celebrate changes in the patient’s condition in response to new treatments. If you can cause change, then you can take control over the problem. Above we’ve listed just five herbs that cure schizophrenia and psychosis, but there are hundreds or perhaps thousands of potential cures to consider. 

Click here to read more about amino acid therapies in the treatment of addictions and mental health issues.


Bagchi, Preenon, and Waheeta Hopper. (2011). Virtual Screening of Active Compounds of Valeriana wallichii, Acorus calamus, and Asparagus racemosus with Schizophrenic Proteins COMT & GRM3. 

Mikami, M. et al. (2021). Acorus calamus extract and its component alpha-asarone attenuate murine hippocampal neuronal cell death induced by l-glutamate and tunicamycin. Retrieved July 17, 2023 from

Ayoka, A. O. et al. (2006). Sedative, antiepileptic and antipsychotic effects of Spondias mombin, L. (Anacardiaceae) in mice and rats. Retrieved July 18, 2023 from

Taiwe, G. S. et al. (2012). Antipsychotic and sedative effects of the leaf extract of Crassocephalum bauchiense (Hutch.) Milne-Redh (Asteraceae) in rodents.  Retrieved July 18, 2023 from

Amoateng, P. et al. (2017). Extract of Synedrella nodiflora (L) Gaertn exhibits antipsychotic properties in murine models of psychosis. Retrieved July 18, 2023 from

Amoateng, P. et al. (2017). An ethanolic extract of Desmodium adscendens exhibits antipsychotic-like activity in mice. Retrieved July 18, 2023 from

Rastogi, S. et al. (2011). An ethnomedicinal, phytochemical and pharmacological profile of Desmodium gangeticum (L.) DC. and Desmodium adscendens (Sw.) DC. Retrieved July 18, 2023 from

Amoateng, P. et al. (2017). Psychotropic Effects of an Alcoholic Extract from the Leaves of Albizia zygia (Leguminosae-Mimosoidae). Retrieved July 18, 2023 from

Kumbol, V. W. A. et al. (2020). Antidepressant-like effect of Albizia zygia root extract in murine models. Retrieved July 18, 2023 from

Abotsi, W. K. M. et al. (2017). An evaluation of the anti-inflammatory, antipyretic and analgesic effects of hydroethanol leaf extract of Albizia zygia in animal models. Retrieved July 18, 2023 from

Saleem, A. et al. (2022). Alternative Therapy of Psychosis: Potential Phytochemicals and Drug Targets in the Management of Schizophrenia. Retrieved July 18, 2023 from

Retrieved July 18, 2023 from file:///Users/jennifershipp/Downloads/528-Article%20Text-1600-1-10-20130514.pdf 
Nkwemeh, C. N. et al. (2023). Anxiolytic effects of an aqueous extract of Crassocephalum bauchiense Hutch (ASteraceae) in mice with possible GABAergic involvement. Retrieved July 18, 2023 from

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