How to Get Rid of Complex PTSD
Agmatine helps increase synaptic connections in the brain. Essentially, thoughts that get "trapped" in a loop pattern due to trauma can find their way through new synaptic connections to a point of resolution using agmatine.What is Agmatine?
Agmatine is a substance that our bodies produce naturally, but that can also be taken as a supplement. Agmatine modulates and balances the glutamatergic system, thus it has slightly different effects in different people depending on what they need. For some, agmatine improves energy levels. For others, agmatine allows the body and mind to relax more easily. Agmatine levels in the brain and body are often low in those who have experienced trauma. Indeed, some scientists have compared the physiological effects of taking agmatine with the physiological effects of ketamine (though agmatine does not produce any dissociative or hallucinogenic effects). As a natural treatment for complex PTSD and PTSD, agmatine can be extremely useful as an adjunct therapy that will allow new brain cells and synaptic connections to open up to help people get out of the dead-end trauma-thoughts that keep the body in a fight-or-flight or "play dead" state. Indeed, while agmatine generally improves learning and memory, this substance has also been shown to reduce memory of auditory and contextual fear conditioning. What this means is that if you have been conditioned to experience a fear response when you're exposed to a "trigger", agmatine can help release this conditioned response so that it no longer triggers you. Click here to read more about what agmatine is and how it works to treat complex PTSD naturally.
Can PTSD be cured?
Though some sources claim (erroneously) that PTSD and complex PTSD are not curable, in reality, both are totally curable and there is a long list of treatments that patients can use to release negative memories that are stored in the body as present-tense “relivings” of the past. Treatments vary in terms of how long they take to produce a PTSD cure and how many treatments are required to get rid of PTSD, but agmatine is a substance that can be administered as an adjunct therapy in combination with any of the various cures for PTSD that are currently known including:
- Psilocybin Therapy
- Use microdosing to release trauma that causes PTSD in small doses. Note that microdosing takes longer to work, but can help you feel better on a day-to-day basis.
- Use macrodosing to release PTSD trauma in bigger doses to make progress more quickly. In our experience, most people should expect to do 20-30 "trips" to overcome PTSD or complex PTSD to a point where they feel mostly normal overall.
- Contact us to schedule a health coaching session or integrative psychotherapy to learn how to use psilocybin properly to treat PTSD at home.
Click here to buy microdosing capsules to treat PTSD using psilocybin.
Click here to buy macrodosing capsules to treat PTSD using psilocybin.
- Craniosacral Therapy
- Eye Movement Desensitization and Reprocessing / EMDR
- Note that EMDR is a type of therapy that can be done in person or online. For individuals who don’t have access to an in-person therapist, consider Online EMDR as an alternative resource.
Click here to do a free trial of EMDR online.
- Iboga / Ibogaine Therapy
- Stellate Ganglion Block
- Online Hypnotherapy and Guided Meditation
- The DreamLight.app is a powerful brain entrainment tool that uses guided meditation and hypnotherapy to access trauma for release. This tool specifically targets health issues that involve both the mind and the body.
Click here to subscribe to the DreamLight.app.
- Neurofeedback Therapy
- Ayahuasca
- Note that Ayahuasca works through several mechanisms of action. As an herbal remedy for diabetes, Ayahuasca can restore normal insulin levels in the body and cellular function. PTSD and diabetes are related health issues. Click here to read more about Ayahuasca as a cure for diabetes.
- Contact us at [email protected] to learn more about Ayahuasca retreats at our facility near Mexico City.
- Kudzu
- Like Ayahuasca, Kudzu appears to work as a cure for PTSD by alleviating issues around blood sugar levels and pancreatic malfunctioning. Click here to read more Kudzu as a cure for diabetes.
- Kambo (Frog Venom Therapy)
- Kambo balances the autonomic nervous system.
- ontact us at [email protected] to learn more about getting Kambo treatments at our facility near Mexico City.
- MDMA Therapy (not available in many countries at the moment)
- Ketamine Therapy
- Nuciferine / Blue Lotus
- Blue lotus can have a powerful centering effect in those with PTSD. Click here to read more about how nuciferine / Blue Lotus works as a cure for PTSD.
- Note that for some people, it may work better to smoke blue lotus than to administer the tincture. When you smoke blue lotus, you are administering apomorphine, a substance that is not an opiate, but that interacts with opiate receptors in the body. Smoke no more than a thimble of the blue lotus petals to treat symptoms of anxiety naturally.
Click here to buy Blue Lotus Tincture.
- 7,8-Dihydroxyflavone
- This is another supportive therapy that helps regrow areas of the brain that have atrophied due to PTSD. Click here to read more about 7,8-Dihydroxyflavone as a cure for PTSD.
Click here to buy 7,8-Dihydroxyflavone.
- Cannabis
- Increases brain alpha states.
- Acorus calamus
- Administer the calamus oil at night to the feet as it is rather stinky.
-
Click here to buy Acorus calamus oil as an herbal remedy for PTSD.
Again, it’s important to note that some of the treatments listed above may have long-lasting effects, but may need to be repeated many times to get rid of complex PTSD or PTSD permanently. Many of the treatments work very slowly over time. Of the treatments listed above, Ibogaine is the most likely to produce dramatic, long-lasting results after one dose as long as the patient works with a treatment such as EMDR following the initial Ibogaine administration. Agmatine can be used as an adjunct therapy with any of the above treatments. Be sure to let healers know if you are taking agmatine prior to being given Kambo, Psilocybin, Ketamine, MDMA, Ayahuasca, or Ibogaine or simply abstain from taking the agmatine for 24 hour prior to treatment with any of these medicines.
Agmatine as a Natural Cure for PTSD and Complex PTSD
Agmatine is a natural substance that the body makes from the amino acid L-arginine. Agmatine has been extensively studied due to its powerful neuromodulation effects and extremely low toxicity. This makes agmatine the ideal supplement for those with PTSD. It is extremely unlikely that agmatine will cause adverse effects, though a small number of people have reported that agmatine can worsen herpes simplex outbreak (if this happens, take an equivalent dose of Lysine along with your agmatine doses – note that certain forms of agmatine can get rid of herpes simplex virus infections over time).
The endogenous agmatine system is essential for normal adaptation to stressful events. It acts to protect the neurons from damage during times of increased stress. It has also been found in increased quantities in individuals with Major Depressive Disorder (MDD) and scientists believe that this happens because agmatine can reduce depression. Both astrocytes and macrophages have increased levels of agmatine under stressful conditions as well. So this is a nutrient substance that naturally mitigates stress in our bodies. When the body’s natural attempt to mitigate stress is overwhelmed, agmatine can be taken as a supplement to prevent PTSD but also to treat existing forms of PTSD including Complex PTSD.
Agmatine has been used to counteract the negative effects of stress and chronically high levels of glucocorticoids at a dose of 10 mg / kg body weight by mouth per day. The administration of this dose of agmatine increases the production of new cells in the hippocampus in chronically stressed mice. Another study showed that this dose of agmatine was able to get rid of the restraint stress-induced depression behavior through its antioxidant activity. So agmatine works through several different mechanisms of action to protect the brain and to target the areas of the brain (i.e. the hippocampus) that are most afflicted in PTSD and Complex PTSD.
Click here to read more about how to rebalance the autonomic nervous system.
Other studies have shown that chronic agmatine administration increases sucrose preference in mice and improves their motivational behaviors and self-care behaviors during an experiment that involved chronic and unpredictable mild stress. Agmatine also normalized elevated corticosterone levels such that body weight changes were prevented in chronically stressed animal models. In individuals with PTSD or Complex PTSD, the autonomic nervous system is not functioning properly. The individual is essentially “frozen in traumatic moments time” such that their bodies behave as though they were reliving the moment of trauma over and over again. The mind searches at times for material in the present-tense that fits with the sensations that the body is feeling which tend to include both a fight-or-flight reflex along with the “freeze” or “play dead” reflex. These autonomic nervous system responses are also responsible for autism and a variety of other neurological problems. Some scientists are studying the cellular basis for these autonomic nervous system problems using substances like Suramin to rebalance cellular response. Click here to read more about Suramin and pine needle teas (from which Suramin is derived) and how it works to restore balance to the autonomic nervous system. Though Suramin has not been studied in terms of its ability to treat PTSD naturally, this substance has been used to treat various health conditions that are closely related physiologically to PTSD.
Click here to buy The Origami of Autism: Transforming 2-Dimensional Thinking about ASD into 3-Dimensional Solutions.
Importantly, agmatine was able to protect hippocampal cells when an animal is under chronic stress. Similar to ketamine, the oral administration of agmatine was able to relieve depression. Scientists who have studied agmatine’s effects on the brain have noted that while agmatine does not cause the same psychoactive effects as ketamine, agmatine has a similar healing effect on the brain as ketamine. And while ketamine is typically administered in a clinical setting, agmatine can be administered daily in a home setting.
One animal study demonstrated that agmatine at a dose of 20, 40, or 80 mg / kg body weight was able to reverse the effects of a single, prolonged exposure to stress if it was administered shortly after the stressful event. Of course, someone with PTSD or complex PTSD may have experienced several or many exposures to extreme, perceived life-threatening situations, but this study shows that agmatine can assist the brain in overcoming these negative memories too. It may take more time for agmatine to work if the memories have been in place for a long time, but for recent traumatic memories, agmatine can help the brain and autonomic nervous system release the effects.
Anecdotal Reports Regading Agmatine for Complex PTSD and PTSD
Anecdotal reports regarding the use of agmatine for Complex PTSD and PTSD indicate that people may be more prone to feeling and expressing their emotions in a more normal way when they take 1000 mg or more agmatine daily. Note that some studies have shown that lower doses of agmatine (10, 20, or 30 mg / kg of body weight) can reduce negative memories that a patient "passively avoids". In contrast, higher doses (40 to 80 mg / kg body weight) improves memory. Though studies that have talked about this effect have been primarily geared at learning and memory, in patients with complex PTSD, lower doses of agmatine may be desirable at first. Over time, as the patient develops resources and tools to naturally reduce the physical response they are having to memory content, the patient may consider increasing the dose up to 3500 mg per day (in divided doses).
Agmatine Dosing for PTSD and Complex PTSD
Click here to read a basic overview of agmatine as a natural supplement for complex PTSD and PTSD along with information about proper dosing.
Click here to subscribe to the Living Database!
Resources:
• Aricioglu, F. (2016). PS52. Effect of agmatine on behavioral changes over time in post-traumatic stress disorder. Retrieved September 30, 2023 from https://academic.oup.com/ijnp/article/19/Suppl_1/92/2946586?login=false
• Uzbay, T. (2012). A new target for diagnosis and treatment for CNS disorders: agmatinergic system. Retrieved September 2023 from https://pubmed.ncbi.nlm.nih.gov/22934767/
• Ostovan, V. R. et al. (2022). The effects of subchronic agmatine on passive avoidance memory, anxiety-like behavior and hippocampal Akt/GSK-3beta in mice. Retrieved September 30, 2023 from https://pubmed.ncbi.nlm.nih.gov/34954711/
