Andrographis paniculata: Killer of Protozoa and Spiral-Shaped Bacteria


What is Andrographis paniculata

Andrographis paniculata is a bitter herb that grows in Asia.It is also known as: 


  • Green Chiretta
  • Creat 
  • Chuan Xin Lian
  • Kalmegh
  • Indian Echinacea
  • “The King of Bitters”. 


Andrographis paniculata is particularly useful as an anti-parasitic, anti-protozoan, and as an herbal remedy for Borrelia burgdorferi infection and Toxoplasmosis as well as Weil’s Disease / Leptospirosis and Helicobacter pylori. Note that Borrelia, Leptospirosis, and Helicobacter bacteria are all spiral-shaped bacteria. Helicobacter bacteria have been studied the most extensively and these bacteria possess some interesting properties that might be used to explain the trajectory of Lyme disease and Weil’s Disease. Because Lyme disease and Weil’s disease have not been studied as well, readers will need to decide whether they want to make the analogy between these various spiral-shaped bacteria or not, but it’s worth stating that people with Toxoplasmosis infection are likely to experience a worsened case of their disease if they have a co-infection with Helicobacter pylori. Luckily, Andrographis paniculata is an herb that can treat all of these diseases. 


Bitter herbs are particularly useful against parasite infections and digestive upsets. But Andrographis paniculata has also proven to be extremely useful as healer of the immune system and can be used as a treatment for autoimmune disease as well. It’s usefulness as a natural treatment for autoimmune disease might be able to be explained best by its ability to kill Helicobacter pylori, a bacteria with shape-changing abilities that make this pathogen resistant to synthetic pharmaceuticals. By changing shape from a spirochete to a coccoid / sphere, this bacteria is able to evade synthetic pharmaceuticals that have been specifically formulated to only be able to kill one form of the pathogen (the spirochete). 


There are a number of experts on alternative cancer cures who have used dark-field microscopy to observe that mycobacterium cause cancer via infection of human cells. Interestingly, a number of these experts including Dr. Livingston-Wheeler, Dr. Isaac Goiz, Dr. Gaston Naessons, and Dr. Royal Rife have all observed this mycobacterium and they also report that these cancer-causing pathogens change shape on the basis of pH levels in the tissues. 

H. pylori, in fact, changes shape as it passes from the acidic outer layer of tissues in the stomach to the inner, more alkaline tissues underneath. 

What are the medicinal benefits of Andrographis paniculata?

Though in this article, we’re primarily focusing on just a few medicinal benefits, Andrographis paniculata actually has an extremely broad spectrum of action as far as herbs go. When we look at herbal cures for disease at AlivenHealthy, we view each plant as a conscious entity and we look at how it treats the body as a sort of “personality profile” for the herb. Andrographis paniculata is an herb that appears to work with shape-changing pathogens while it protects the liver and lymphatic system from new colonizations by autoimmune-causing bacteria. Through its lymphatic system function and its ability to pass the blood-brain barrier, Andrographis paniculata is able to treat nearly every organ and system in the body that might be infected with colonies of bacteria, mycobacteria, viruses, and protozoa.  


Below is a list of the incredibly long list of diseases that can be treated using Andrographis paniculata:


    • Cancer
      • Leukemia
      • Kidney Cancer
      • Pancreatic Cancer
      • Colon Cancer
      • Melanoma
      • Glioblastoma multiforme
      • Lung Cancer
      • Brain Cancer
      • Breast Cancer
    • Leprosy / Hansen’s Disease
    • Digestive Diseases
      • Inflammatory Bowel Diseases (Crohn’s Disease, Ulcerative Colitis)
      • Colitis
      • Diarrhea
      • Gas
    • Hypertension / High Blood Pressure
    • Multiple Sclerosis
    • Diabetes
    • Arthritis / Joint Inflammation
    • Skin Diseases
      • Eczema
      • Skin Ulcers
    • Bacterial Infections
      • Borrelia infection / Lyme Disease / Bartonella
      • Weil’s Disease / Leptospirosis
      • Pseudomonas aeruginosa infection
      • Pneumonia
      • Helicobacter pylori
  • Parasite Infections
    • Leishmaniasis
    • Toxoplasmosis
    • Malaria
  • Viral Infections
    • Mumps
    • Chickenpox
    • Dengue
    • Influenza
    • Common Cold
    • COVID-19
  • Fever
  • Pain Control
  • Ear Infection
  • Inflammatory Diseases
  • High Blood Pressure
  • Canker Sores
  • Metabolic Disease
  • Tonsilitis
  • Kidney Disease
    • Kidney Stones
  • Lung Disease 
    • Bronchitis
  • Toxoplamosis gondii
  • Insect Stings (topical)
  • Snakebites
  • Sepsis / Blood Infection
  • Low Immunity / Immune Suppression 
  • Autoimmunity
    • Vitiligo
    • Autoimmune Hepatitis
    • Fibromyalgia
    • Diabetes
  • Liver Congestion
  • Headache
  • Liver Damage
  • Jaundice
  • Abscess
  • Urinary Tract Infection (UTI)
  • Hepatitis 
    • Viral Hepatitis
  • Heart Disease
    • Heart Attack Prevention
  • Gonorrhea
  • Sexual Dysfunction / Low Libido
    • Low Testosterone Levels
    • Erectile Dysfunction
    • Menstrual Cramps

Andrographis paniculata and Siberian Ginseng (Eleutherococcus senticosus)

Andrographis paniculata is often combined with Siberian Ginseng and if you’re looking into herbal remedies for toxoplasmosis, Lyme Disease, Leptospirosis, or Autoimmune Disease, consider combining Andrographis paniculata with Siberian Ginseng to improve its immune boosting effects. 

Andrographis paniculata as an Herbal Remedy for Lyme Disease

Lyme disease is caused by the spiral-shaped bacteria known as Borrelia burgdorferi or Borrelia mayonii. In the early stages of the disease, the planktonic stage, Andrographis paniculata works by supporting the immune system. In later stages of the disease, it works through several different mechanisms of action to reduce inflammation in the joints and connective tissue. 


Andrographis paniculata is an herbal remedy for mumps, which demonstrates its ability to work with the lymph nodes, which are often inflamed in those with Lyme disease. Through its ability to work in the lymphatic system, Andrographis paniculata is able to use its anti-bacterial, anti-Borrelial capabilities to get rid of the bacteria where it lives and thrives. 


Additionally, Andrographis paniculata is able to support the liver and the gallbladder, both of which are common reservoirs for bacteria that take up long-term residence in the body to cause autoimmune disease symptoms. But this herb is unique in terms of its ability to work on multiple systems of the body, as demonstrated by the diseases listed above that can be treated using this herb. Note that Andrographis paniculata is able to treat both heart disease as well as sexual dysfunctions and bladder issues. But it also has the ability to work on the lungs, the digestive system, the brain, and the immune system. So this is a good herb to work with if you feel like you’re falling apart. Andrographis can strengthen the heart, the liver, the lungs, and digestion as well as reproductive organs. 


Don’t expect for this herb to work like a drug. Many people give up too early on herbal treatment or they take the wrong dose. Herbs work to cure the body of disease, so they need time to work. Many people who have had Lyme disease for a period of time know that moving to quickly with treatments can cause uncomfortable detox reactions. Herbal remedies for Lyme disease have an advantage over other forms of treatment because, if you take the proper dose, they tend to be very gentle in terms of how they work. Andrographis paniculata is no exception. An herb that works on so many different parts of the body and healing at the same time needs to be given several months to demonstrate what it can really do. 


How Andrographis Paniculata Works as a Natural Treatment for Lyme Disease

If you’re using this herb to treat Lyme disease, then it would be helpful for you to understand what its doing inside your body when you take it, so below, we’ve listed how Andrographis paniculata will work with you body to combat the disease:


  • Kills the Borrelia burgdorferi or Borrelia mayonii spirochetes
  • Reduces inflammation in the joints
  • Easily crosses the blood brain barrier and accumulates in the Central Nervous System tissues to kill Borrelia bacteria living in the brain and nervous system tissues.
  • Reduces inflammation in the Central Nervous System
  • Acts as a sedative with calming effects on the body
  • Reduces headaches
  • Reduces chronic fatigue
  • Reduces confusion
  • Stimulates the body’s natural immune response to the infection
  • Modulates the immune system response
  • Improves liver functioning by killing spirochetes that may be living in the liver and gallbladder.
  • Protects the liver and gallbladder against new infection.
  • Protects the heart muscle.


Note that Andrographis paniculata can be used to treat three hard-to-treat bacterial infections that are caused by bacteria that have a spiral shape: 1) Borrelia burgdorferi / Borrelia mayonii 2) Helicobacter pylori and 3) Leptospirosis.


Detoxification Symptoms Associated with Taking Andrographis paniculata as an Herbal Remedy for Lyme Disease

Andrographis paniculata can cause a variety of detox symptoms as it clears the body of disease. In other words, you might feel worse before you feel better, but give this herb time to work in the body and reduce the dosage by half if you experience a detox reaction, but continue taking it. Resume the higher dosage when symptoms go away. Below are detoxification symptoms to expect while taking Andrographis paniculata as an herbal remedy for Lyme disease:


  • Constipation
  • Gastric upsets (in very high doses)

Who Should Avoid Taking Andrographis paniculata?

Do not take A. paniculata if you are pregnant because it inhibits production of progesterone, which can cause miscarriage or stillbirth. It is a contraceptive herb and an abortifacient. Andrographis paniculata can also reduce sperm production. After treatment, however, sperm production returns to normal. 


Andrographis paniculata may increase the potency of isoniazid, a drug used to treat tuberculosis. A. paniculata and isoniazid should not be used together. 

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Andrographis paniculata as a Natural Treatment for Toxoplasmosis

Andrographis paniculata is one of several herbal remedies for Toxoplasmosis, malaria, and other types of protozoa infections. It has also been used as a cure for Lyme disease. This plant has a broad spectrum of action and it works in part by releasing antioxidants as well as medicinal Reactive Oxygen Species such as Hydrogen Peroxide and superoxide anions along with nitric oxide into the body. There are other powerful herbal remedies for parasite infection that release Reactive Oxygen Species such as hydrogen peroxide like Artemisia annua. This particular mechanism of action resembles that of Chlorine Dioxide Solution (CDS) / Miracle Mineral Supplement and lends credibility to the idea that any of these Reactive Oxygen Species medicines could be valuable as treatments against Toxoplasmosis as well as Lyme disease. 


But Andrographis paniculata may work through another mechanism of action that could explain why it has the ability to get rid of a Toxoplasmosis infection. Andrographis paniculata is able to protect the liver / gallbladder, which are organs that are often colonized by certain types of bacteria that then lower resistance to other types of pathogens such as protozoans (i.e. Toxoplasmosis). It has an immunostimulating effect on the body, but it also modulates reproductive hormone levels, which play a key role in immune system function as well. 



Below we talk about Andrographis paniculata as an herbal remedy for H. pylori infection. Note that co-infection of Toxoplasmosis with H. pylori can cause more severe symptoms, specifically neurological symptoms. Clearing up an H. pylori infection can help the body overcome a Toxo infection.


Andrographis paniculata as an Herbal Remedy for Helicobacter pylori

Studies have shown that Andrographis paniculata is able to inhibit the growth of Helicobacter pylori, a bacteria that lives in the stomach and that causes gastric ulcers as well as stomach cancer. Apparently, Andrographis paniculata inhibits the production of urease, a substance that enhances the survival of Helicobacter pylori and it also has the ability to kill the bacteria itself. 


Helicobacter pylori is a spiral-shaped bacteria that has been studied extensively because it is present in many municipal water supplies and must be managed throughout the world. Nonetheless, about 50% of the population of the world is infected with H. pylori. It is a difficult bacteria to kill because it has the ability to use its spiral shape to burrow into stomach tissues to escape from high acid levels and find more suitable, alkaline tissues below. H. pylori is also one of few bacteria that has been studied enough for scientists to observe its ability to change shape depending on the pH level of its surroundings.


Though the Borrelia bacteria and Leptospiro bacteria have not been observed changing shape to escape drug treatment using synthetic pharmaceuticals, it’s likely that they have these pleiomorphic abilities too. Herbal treatments for shape-changing bacteria tend to be far more effective than drug treatments because the plants are calibrated to work with all forms of the bacteria to get rid of them. 


Note that autoimmune diseases like Lupus can be exacerbated by bacteria like Helicobacter pylori but that there are a number of cures for an H. pylori infection. Some of these cures may also be relevant to the other spiral-shaped bacteria in this article (Borrelia and Leptospirosis)


Andrographis paniculata as a Natural Treatment for Leptospirosis / Weil’s Disease

Leptospirosis, also known as Weil’s Disease, is a zoonotic disease caused by bacterial spirochetes known as Leptospira. One scientific study evaluated 11 different herbal extracts to examine their anti-leptospiral activity. Only one extract had both anti-leptospiral activity as well as immune enhancing abilities: Andrographis paniculata. This herb had anti-leptospiral activity against all of the species of Leptospirosis that were tested in the study. Scientists noted that the ability of Andrographis paniculata to achieve broad distribution throughout the body and tissues as well as its liver-protective abilities made it the ideal herbal treatment for Leptospirosis. 


Note that both Leptospirosis, Helicobacter pylori, and the Lyme disease bacteria all have the spirochete shape.


Andrographis paniculata Dosage: 

It’s important to find a product that contains a high concentration of andrographolides to ensure that the supplement is high-quality and that it will work, as promised. Look for somewhere between 10% and 30% concentration of andrographolides.


If you purchase a product with 10% andrographolides, take between 300 to 400 mg daily. If you purchase a product that contains a higher concentration of andrographolides, decrease the dose to reflect the higher concentration (30% concentration extracts would mean that you’d take 100 mg daily, for example).


If you use the actual dried plant, pound about 20 grams of the herb, mix it into water so that the herb is fully covered, let it sit overnight and then filter it and put the leftover water in the refrigerator. Administer 40 mL of this infusion by mouth, twice daily. 


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Other Important Links:

Infection or Immune Dysfunction: Is there a cure for toxoplasmosis?

Reframing Toxoplasmosis: How to Reduce Toxicities, Restore Cellular Health, and Rebuild the Immune System to Fight Toxoplasmosis

Herbal Cures for Toxoplasmosis and Other Parasitic Infections

How to Prevent Long COVID after COVID-19 Infection: Modified Citrus Pectin

Modified Citrus Pectin as a Natural Treatment for Lyme Disease

Rife Therapy Cure for Lyme Disease, Toxoplasmosis, Liver Flukes, Tapeworm / Neurocysticercosis, and Other Parasite Infections

Toxoplasmosis Diet: Cure Toxoplasmosis Gondii Using Healthy Fats and Oils

Food Grade Hydrogen Peroxide as a Cure for Crohn’s Disease and Ulcerative Colitis

Sweet Wormwood (Artemisia annua) and Artemisinin as a Cancer Cure

Introduction to Chlorine Dioxide

How to Get Rid of H. Pylori Naturally: Basic Protocol

Lupus and Helicobacter pylori: Hydrochloric Acid Supplements for SLE



Okhuarobo, A. et al. (2014). Harnessing the medicinal properties of Andrographis paniculata for diseases and beyond: a review of its phytochemistry and pharmacology. Retrieved July 16, 2022 from 


Researched (2021). Andrographis Paniculata for Killing Common Colds and Slowing Cancer Proliferation. Retrieved July 16, 2022 from 


Yue, G. G. L. et al. (2015). Andrographis paniculata elicits anti-invasion activities by suppressing TM4SF3 gene expression and by anoikis-sensitization in esophageal cancer cell. Retrieved July 16, 2022 from 


LymeGuide (2017-2021). Andrographis (Lat Andrographis paniculata.) Retrieved July 16, 2022 from ​​ 


Murugesan, A. C. et al. (2011). Anti-leptospiral activity of Andrographis paniculata extract. Retrieved July 16, 2022 from 


Shaikh, R. U. et al. (2016). Inhibition of Helicobacter pylori and Its Associate Urease by Labdane Diterpenoids Isolated from Andrographis paniculata. Retrieved July 16, 2022 from 

Ramalingam, S. et al. (2018). Anti-dengue activity of Andrographis paniculata extracts and quantification of dengue viral inhibition by SYBR green reverse transcription polymerase chain reaction. Retrieved July 16, 2022 from 


Rafi, M. (2020). Classification of Andrographis paniculata extracts by solvent extraction using HPLC fingerprint and chemometric analysis. Retrieved July 16, 2022 from