Qingdonghuoxue / Qingre huoxue 


Qingdonghuoxue (also known as Qidong Huoxue or Qingre huoxue)  is an herbal remedy for pulmonary edema that is used in Traditional Chinese Medicine. It is also often prescribed to treat:

  • Acute Respiratory Distress Syndrome (ARDS)
  • Rheumatoid Arthritis
  • Heart Attack / Myocardial Infarction
  • Heart Disease
  • Cytokine Storm
  • Atherosclerosis





Qingre huoxue is a mixture of several different herbs including:

  • Ligusticum wallichii (chuanxiong)
  • Radix Paeoniae Rubra (chishao)
  • Lignum acronychiae (jiangxiang)
  • Safflower (honghua)
  • Salvia miltiorrhiza (danshen)
  • Scutellaria baicalensis (huanggin)
  • Ilex pubescen (mao dong qing)



Qingre huoxue is also employed to treat acute lung injury and acute respiratory distress syndrome (ARDS) as well as rheumatoid arthritis and heart attack / myocardial infarction. This herbal remedy works by reducing pro-inflammatory cytokine levels that contribute to lung inflammation, thus getting rid of pulmonary edema.  It clears heat (according to the TCM model of medicine) and promotes blood circulation. 


Qingre Huoxue has also demonstrated the ability to cure atherosclerosis in mice models of the disease. As such this herbal treatment would best be applied to patients who are experiencing lung edema and who are also suffering from atherosclerosis. But Qingre Huoxue also protects heart tissues by inhibiting certain inflammatory factors that play a role in heart disease.



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Qui, R. et al. (2019). Yangyin Quingre Huoxue Method in Traditional Chinese Medicine Ameliorates Atherosclerosis in ApoE-/- Mice Suffering from High-Fat Diet and HSP65 Aggression. Retrieved April 26, 2022 from https://pubmed.ncbi.nlm.nih.gov/30713570/ 


Gong, X. et al. (2021). Traditional Chinese Medicine Qingre Huoxue Treatment vs. the Combination for Methotrexate and Hydroxychloroquine for Active Rheumatoid Arthritis: A Multicenter, Double-Blind, Randomized Controlled Trial. Retrieved May 3, 2022 from https://pubmed.ncbi.nlm.nih.gov/34113254/ 


Jin, Z. et al. (2021). Protective effect of Qingre Huoxue decoction against myocardial infarction via P13K/Akt autophagy pathway based on UPLC-MS, network pharmacology, and in vivo evidence. Retrieved May 3, 2022 from ​https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8635559/ 


Jia, C. et al. (2019). Study on the mechanism of quingre huoxue prescription in the intervention and treatment of acute myocardial infarction based on network pharmacology. Retrieved May 3, 2022 from https://www.researchgate.net/publication/334885340_Study_on_the_mechanism_of_qingre_huoxue_prescription_in_the_intervention_and_treatment_of_acute_myocardial_infarction_based_on_network_pharmacology