Modified Citrus Pectin to Reduce Cytokine Storms, Prevent Long COVID, and Diminish Symptoms of COVID-19 Infection

What is modified citrus pectin?

Pectin is a common fiber found in most fruits, though it is found in the highest quantities in apples, plums, and the pulp and peel of citrus fruits like oranges, grapefruit, lemons, and limes. This substance is what makes jams and jellies have their expected thick texture. By itself, pectin cannot be absorbed by the body, however modified pectin (specifically modified citrus pectin) has been altered in such a way that it can be absorbed, digested, and utilized more easily. 


Modified citrus pectin (MCP) is sold as a nutritional supplement in health food stores and online. It may be most effective when used in combination with a healing protocol that utilizes various complementary therapies for the treatment of Long COVID or COVID-19. 

Uses of Modified Citrus Pectin

Modified citrus pectin has been shown to play a role in the treatment of various illnesses, including (but not limited to): 

  • Cancer
  • Cardiovascular disease
  • Kidney disease
  • Heavy metal poisoning
  • Detoxification
  • Herpes
  • Hepatitis
  • Influenza
  • Mosaic disease
  • COVID-19
  • Lowers cholesterol levels
  • Fibrosis
  • Chronic inflammation
  • Anti-aging
  • Lyme disease
  • Atherosclerosis
  • Drug-resistant MRSA


Modified citrus pectin is notable in large part because of its ability to block Galectin-3, a pro-inflammatory protein responsible for the production of biofilm. The Gal-3 protein can drive the development of tumors, perpetuate chronic inflammation, and lead to fibrosis and immune suppression. In cases where the body is facing illness, injury, stress, or aging, this protein is more likely to be secreted in order to try and heal whatever sickness the body is currently dealing with. However, unfortunately, Gal-3 can often have unwanted effects if it is produced excessively. 


Biofilm is a sticky substance that forms a barrier around infections, tumors, and injuries in order to prevent the illness from spreading to other parts of the body. Although this function of biofilm is important, biofilm’s presence can also make it difficult (if not impossible sometimes, depending on the situation) for medicines to reach the covered up areas of the body in order to heal them. Thus, if biofilm is allowed to stay in place, some pathogens can remain safely covered up in the body for long periods of time. This means that even if you’ve successfully treated the pathogen in other areas of your body, there may still be pockets where the infection is hiding out. These pockets of infection hidden underneath biofilm can lead to feelings of fatigue or brain fog, or to ongoing, undesirable digestive symptoms. 


In the treatment of disease, reduction of inflammation and strengthening and modulation of the immune system are both extremely important actions, making MCP a compelling natural medicine for the treatment of various diseases. There are many different illnesses whose cause can often be traced back to the presence of biofilms, including many of those listed above, and MCP’s ability to break up biofilm makes it a worthy treatment option for a variety of problems. In addition, after the MCP dissolves the biofilm coating covering up areas of infection or toxicity in the body, it also helps “mop up” the remaining toxicities and carry them out of the body, thus resulting in a less intense detox process. 


Modified Citrus Pectin for COVID-19 and Long COVID

In the treatment of COVID-19, modified citrus pectin may be a valuable treatment for COVID cytokine storm syndrome. During a cytokine storm, there is excess inflammation in the body that can cause damage to tissues (specifically in the lungs in the case of COVID) if left unchecked. Because one of MCP’s primary roles is to bring down inflammation, it can be a valuable therapy to help people with COVID-19 recover fully from the infection as well as to stop the cytokine storm. If you plan to use MCP to treat or prevent a cytokine storm, you should wait to administer it until after Phase 1 of the COVID-19 infection. 


COVID-19 patients tend to have higher levels of the Gal-3 protein, which is also known to increase levels of pro-inflammatory cytokines like TNF-alpha and IL-6. By blocking the production of Gal-3, the production of some of these other cytokines implicated in tissue damage during cytokine storms may also be inhibited. 



Modified citrus pectin is also valuable for the prevention of both primary and secondary COVID-19 infections. The protein Gal-3 plays an important role in allowing the SARS-CoV-2 virus to invade cells and replicate itself in the body. Specifically, Gal-3 is necessary in order for the virus to be able to attach to the surface of a host cell using the spike protein. Without enough Gal-3, the COVID virus is at a serious disadvantage. MCP’s ability to prevent the production of Gal-3 means that it can also help prevent the replication of the COVID-19 virus. In addition, MCP dissolves biofilms so that the virus is unable to take up residence in any corner of the body (meaning it’s more likely that you’ll actually recover and not end up with Long COVID or a “secondary” infection). 


MCP can help treat Long COVID by removing biofilm in the body and releasing toxins or pathogens that may be slowing you down. Many chronic illnesses, including chronic fatigue syndrome (which shares many similarities with Long COVID), are caused by the presence of biofilm. In addition, MCP will help reduce any remaining inflammation in the body that may be causing pain or discomfort. 


Dosage and Administration Methods

Modified citrus pectin is usually administered either in a capsulized form or as a powder that can be added to and dissolved in water. The ideal dosage for cancer and cancer metastasis treatment is 15 grams daily, though it may be administered at any amount between 5 grams to 15 grams depending on individual needs. We recommend starting with the lower dose of 5 grams to see how your body responds, and then increase the dosage over the course of a week to the full 15g per day dosage. You should take this dose of MCP for between 2-4 weeks. 


The most common brand of MCP is called PectaSol, and is the primary form of MCP in the United States. Depending on where you are located, you may have access to other brands of modified citrus pectin.


Contraindications and Safety Notes

For some people, taking larger doses of MCP may cause stomach upsets, diarrhea and/or constipation, gas, or bloating. Some individuals may also experience stomach cramps. 


People with an allergy to citrus fruits should not take modified citrus pectin as it may cause an allergic reaction. If you have previously experienced a sensitivity to citrus fruits (or other pectin-containing fruits, like apples), start slow with MCP and work your way up with the dosage. Pay close attention to how you feel, and lower the dosage or stop taking the modified citrus pectin if you experience constipation or other uncomfortable digestive symptoms. 


MCP can interfere with the absorption of medications like Digoxin, Lovastatin, and tetracycline antibiotics, so people who are currently on these medications should use modified citrus pectin with caution. 



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Eliaz, Issac MD, MS, LAc (2020) Not Getting Better with Treatment? Time to Target Biofilms.  Retrieved November 26, 2021 from: https://draxe.com/health/biofilms/ 


Odun-Ayo, Frederick and Reddy, Lalini (2021). Potential Roles of Modified Pectin Targeting Galectin-3 against Severe Acute Respiratory Syndrome Coronavirus-2. Retrieved November 29, 2021 from: ​ https://www.mdpi.com/2571-8800/4/4/56 


McMillen, Matt (2021). Pectin. Retrieved November 29, 2021 from: https://www.webmd.com/vitamins-and-supplements/pectin-uses-and-risks 

Fuchs, Nan Kathryn Ph.D (2003). Modified Citrus Pectin (MCP): A Super Nutraceutical. Retrieved November 29, 2021 from: https://books.google.com.mx/books?id=VP34JeSBzqYC&printsec=frontcover&dq=modified+citrus+pectin&hl=en&sa=X&redir_esc=y#v=onepage&q=modified%20citrus%20pectin&f=false