I Have Cracks at the Corners of My Mouth: What Should I Do?

Disclaimer: Consult with a doctor before deciding on a treatment plan for angular chelitis or any other disease.

There are a number of different things that can cause cracks at the corners of the mouth. This condition is known as either “Perleche” or “Angular Cheilitis”. The issues that can lead to this problem range from vitamin and mineral deficiencies to fungal, staphylococcal, or streptococcal infections. In this article, I’m going to talk about a comprehensive protocol that you can follow to get rid of cracks at the corners of the mouth. This protocol includes 3 different facet. One facet treats vitamin and mineral deficiencies, another treats potential bacterial infections, and yet another treats potential fungal infections.

Cracks at the Corners of the Mouth: Vitamin Deficiencies and Deficiencies of Other Nutrients


Cracks at the corners of the mouth might be caused by any of the following vitamin or mineral deficiencies:


  • Zinc deficiency
  • Iron deficiency
  • Vitamin B2, B3 B5, B6, B9, and/or B12 deficiency 


Vitamin B12 deficiency is particularly noteworthy as a potential cause behind cracks at the corners of the mouth. In fact deficiencies of any of the B vitamins can lead to a variety of serious health issues and, in fact, these deficiencies are relatively common. Vitamin B12 deficiency is extremely common among adults over age 50 and doctors often confuse this deficiency with different types of dementia from Parkinson’s and Lewy Body Dementia to Alzheimer’s Disease.

Deficiencies of the other B vitamins can lead to various mental health issues as well as physical debilitation. Correcting vitamin B12 deficiency often must be done using injections because the deficiency, especially in older adults, results from a lack of intrinsic factor, a substance that must be present in the stomach in order to absorb this vitamin. Older adults naturally have less intrinsic factor which is why doctors used to administer vitamin B12 shots every time patients over 50 years of age came in for a check-up even if they didn’t have vitamin B12 deficiency symptoms. Today, Big Pharma has decided to cash in on vitamin B12 deficiency and the fact that most of the public doesn’t know how this deficiency can ruin a person’s life. 


If your doctor won’t give you a vitamin B12 injection, seek out veterinary products that are safe for human use instead or go to a boutique Intravenous Medicine spa where they do Myer’s Cocktails that contain vitamin B12. Some of these walk-in IV clinics do push-injections of B12 vitamins and you can request them directly, but these clinics are only available in bigger cities in the U.S. In a pinch, you could seek out a B Complex intramuscular (IM) injection product for animals. Exercise caution if you go this route. I have to, as a disclaimer, remind you to only use veterinary products at your own risk.

Consider using Durvet at a dose of 0.5 mL or 1 mL as an intramuscular injection to the deltoid muscle at the top of the arm or to the gluteal muscles. Watch a YouTube video on how to do an intramuscular injection before medicating yourself in this way.


Take a high-quality zinc and iron supplement in addition to working to correct vitamin B deficiencies that may be causing the painful cracks at the corners of the mouth.

Bacterial Infection Treatment: Cracks at the Corners of the Mouth


When an infection is causing the cracks at the corners of the mouth, you might see some yellow crust on the skin, blisters, or you might experience mouth soreness. There are two common germs that cause infection that can lead to cracks at the corners of the mouth:



  • Staphylococcus aureus
  • Beta-hemolytic Streptococci


Herbal Treatment for Cracks at the Corners of the Mouth:

One case study found that a case of recurrent exfoliative cheilitis (cracks at the corners of the mouth) responded well to a treatment with Calendula officinalis. Calendula is the common marigold, but this flower has the ability to heal all kinds of skin infections. In the case of this patient, who was 18 years old and a native of Brazil, the chronic dry scaling on his lips caused him a lot of distress in terms of his appearance. He’d tried corticoid therapy without success. So the doctors prescribed Calendula officinalis ointment at 10% concentration to be used as necessary. The results were striking and the patient recovered quickly.

Fungal Infection Treatment: Cracks at the Corners of the Mouth


Another common reason why people have painful cracks at the corners of the mouth is because of a fungal infection. Candida albicans is a common cause behind Angular Chelitis. If you aren’t sure whether you have a fungal infection or a bacterial infection that’s causing you problems, you can go ahead and treat yourself for both fungal and bacterial infection at the same time. You can do this, by giving yourself an anti-fungal treatment either at noon or right before bed, an hour or two after doing your anti-bacterial treatment.


  1. In a glass container, combine the following ingredients:
  2. Organic Coconut Oil – 2 tablespoons
  3. No Odor DMSO –  1 tablespoon
  4. Bentonite – 2 tablespoons (this is an edible clay that pulls hyphal Candida out of the body through a sort of magnetic process).
  5. Apply a small amount of this mixture to the corners of the mouth 1-2 times per day.



If you believe that you have a Candida albicans infection in your mouth, it’s likely that this infection is causing other health issues like fatigue, foggy thinking, general malaise, panic attacks and anxiety, etc. You can read more here about how to clear up a systemic Candida infection. If you aren’t sure whether you have a fungal infection or a bacterial infection, use both the DMSO+Colloidal Silver protocol and the Coconut Oil + DMSO + Bentonite protocol at separate times of the day to treat for both problems at the same time.

Other Important Links:

How to Cure Candida

Vitamin B12 Deficiency: What Every American Needs to Know 

Fumaric Acid Treatment for Psoriasis

What is Chlorine Dioxide: Bleach or Medicine?: The Chemistry of Miracle Mineral Solution


Wikipedia (2021). Angular Chelitis. Retrieved May 28, 2021 from https://en.wikipedia.org/wiki/Angular_cheilitis 

Miller, N. (2020). B Vitamins: Causes and Symptoms of Deficiency. Retrieved May 28, 2021 from https://www.everlywell.com/blog/b-vitamins/4-top-causes-of-vitamin-b-deficiency/

Doley, J. C. (2021). Cracked Corners of the Mouth: Understanding Angular Chelitis or Perleche. Retrieved May 28, 2021 from https://www.deardoctor.com/inside-the-magazine/issue-15/cracked-corners-of-the-mouth/

Atiyeh, B. S., Costagliola, M., Hayek, S. N., Dibo, S. A. (2006). Effect of silver on burn wound infection control and healing: Review of the literature. Retrieved May 28, 2021 from https://pubmed.ncbi.nlm.nih.gov/17137719/#:~:text=At%20present%2C%20silver%20is%20reemerging,agent%20for%20burn%20wound%20treatment

Roveroni-Favaretto, L. H. D., Lodi, K. B., Almeida, J. D. (2009). Topical Calendula officinalis L. successfully treated exfoliative cheilitis: a case report. Retrieved June 14, 2021 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2803874/?tool=pmcentrez