Antiobiotics for H. pylori
DISCLAIMER: CONSULT WITH A DOCTOR BEFORE DECIDING ON A TREATMENT PLAN FOR ANY DISEASE OR INJURY.
When I was a kid, my Dad had stomach ulcers. We all thought it was due to stress. Occasionally, his stomach problems would flare up and no one questioned the idea that it was due to emotional overload. As I got older, I knew more and more people with this problem. Even as a teenager, I had friends with stomach ulcers that were “due to stress”.
Then I went off to college. Several years into my pre-med program, I took a microbiology class where I learned about Helicobacter pylori, the bacteria that causes stomach ulcers. The information hit me like a revelation. H. pylori was a bacterium that was identified for the first time by Barry J. Marshal and Robin Warren in 1982, just a few years before I went to college and took that microbiology class. A scientist named Stewart Goodwin further investigated H. pylori and discovered its role in chronic gastritis and gastric ulcers. I called home to tell my parents the good news, but by that time, Dad had already been prescribed Tagamet for his heartburn and he didn’t want to hear any new theories on his health problem. He was quite happy about the results of this band-aid treatment.
Tagamet (Cimetidine) was one of the first Blockbuster Drugs ever put on the market by Big Pharma. Everyone and their dog got a prescription for Tagamet back in those days. And while the H. pylori research seemingly promised to rid the world of stomach cancer and gastric ulcers, there were bigger forces at play that saw how this news about infection as an underlying cause for things like gastric reflux, gastritis, and a variety of other stomach issues, would totally ruin the profit margin of these diseases and disorders. Today, there’s an array of Proton Pump Inhibitors (PPIs) and antacids on the market, but doctors and normal, average people really don’t talk much about Helicobacter pylori as a possible cause for heartburn or other stomach-related ailments. And if you’re one of the unlucky few who get stomach cancer or a bleeding ulcer, young doctors won’t blame Helicobacter pylori for the problem as I learned from personal experience when my Mom nearly died of a bleeding ulcer in 2016; they’ll blame NSAIDs, as the underlying cause for the development of stomach ulcers (essentially they’ll blame the patient for their stomach problems). The idea that stomach problems might be caused by Helicobacter pylori, an infection that’s estimated to affect at least half of the population of the world, has been swept under the rug. It doesn’t matter. No one wants to hear about it.
Helicobacter pylori is a major health problem worldwide. At least 50% of the world’s population is infected with H. pylori! People who work with water treatment and purification systems in both developed and undeveloped parts of the world know that H. pylori presents special issues. It’s harder to kill H. pylori than E. coli because H. pylori is so adaptive. It knows how to survive in the harsh environment of the stomach even though it doesn’t really even like acidic environments.
H. pylori bacteria are like the Canadians. I mean, why would anyone decide to live in a cold, dark place like Canada? But Canadians have set up shop up there. They’ve built special houses to withstand the snow and they’ve created electrical grids to keep their houses warm and well-lit through the long, dark winters. They wear their big coats and their earmuffs and they’ve built all this infrastructure to get from place to place in their big 4-wheel drive vehicles. And the final toll on the planet in terms of pollution and destruction of the Canadian forests and landscape has been pretty devastating. (HINT: This paragraph is not really about Canadians.)
So what are we going to do about the Canadians (H. pylori)?
If you go to your doctor about H. pylori, they’ll give you a drug protocol that includes about 17 pills and treatments that will turn your tongue black, the equivalent of setting off an atom bomb in Canada (your digestive system). And at the end of that “treatment regime”, there will still be Canadians living underground who will come out of hiding and start building again as soon as the sun rises again over the nuclear wasteland.
They are, after all, Canadians. They adapt. And they survive.
Remember though, the most common way for Conventional Medicine to deal with Canadians is to deny that they exist. I mean, if you deny that Canadians exist, the people who own the power grids in Canada are really happy about that (Big Pharma) because they make a lot of money keeping those Canadians all warm and cozy in their well-lit little houses.
But back to the real world.
Normal, average people never really knew about H. pylori and how it affects the digestive system to cause problems like Gastroesophageal Reflux Disease (GERD), heartburn, peptic ulcer, gastritis, hives (Chronic Idiopathic Urticaria), motion sickness, morning sickness, migraine headaches, and more. Instead of treating H. pylori as an infection that can be eradicated to heal any of the health problems just mentioned, doctors are educated to cover up the symptoms. It’s not their fault. This is what medical schools teach doctors to do.
But if you suffer from GERD, heartburn, peptic ulcer, gastritis, severe motion sickness, migraines, morning sickness, hives (Chronic Idiopathic Urticaria), or angioedema then you might want to consider the role of H. pylori in your life. This is a microorganism that infects 1 out of 2 people in the world. How that infection is expressed varies from person-to-person though. Some people experience few or transient symptoms of infection while others suffer daily without ever realizing that H. pylori has colonized their stomach and their lives.
Diseases Caused by Helicobacter pylori Infection
Note the other diseases and disorders that may also be caused by a Helicobacter pylori infection:
- SIBO (Small Intestine Bacterial Overgrowth)
- Gastric adenocarcinoma (Gastric cancer)
- Digestive system ulcers (gastric ulcer, peptic ulcer, duodenal ulcer, etc.)
- GERD (Gastroesophageal Reflux Disease)
- Insulin resistance – Studies have shown that people without other H. pylori infection symptoms may develop insulin resistance that leads to atherosclerosis, diabetes II (Diabetes Mellitus), non-alcoholic fatty liver disease, and cardiovascular diseases
- Cardiovascular disease
- Non-alcoholic fatty liver disease
- Diabetes Mellitus (Diabetes Type II)
- Low stomach acid
- Chronic Fatigue
- Motion Sickness
- Morning Sickness (including hyperemesis gravidarum)
- Chronic Idiopathic Urticaria – Secretion of stomach acid in the stomach is triggered by histamine, a compound that’s involved in local immune responses that cause things like rash.
- Unexplained refractory iron deficiency anemia
- Idiopathic Thrombocytopenia Purpura
- Pneumonia (due to Proton Pump Inhibitor use)
If you want to cure GERD, or cure Chronic Idiopathic Urticaria, or get rid of motion sickness permanently, then you need to know something about Helicobacter pylori.
The truth is, this is not an easy infection to treat using Conventional Medicine which requires the combined use of at least 2 to 3 antibiotics (usually metronidazole and clarithromycin or amoxicillin) taken at the same time along with a Proton Pump Inhibitor (PPI) like (omeprazole, lansoprazole, pantoprazole, etc.). This regimen reportedly gets rids of the infection in about 81% of cases, leaving the other 19% of folks in a situation where they can either take more antibiotics along with additional medications that may very well leave them with leaky gut and some kind of autoimmune disease, or they can do some research to find an article like this one that might actually help them cure H. pylori without making their overall health worse than it was when they first went to the doctor. H. pylori is resistant to a lot of the pharmaceuticals that are used to treat it, but it is much less resistant to plant-based medicines combined with orthomolecular medicine (in this case high-dose vitamin C) plus pH Therapy (alkalizing the stomach environment). But before you worry about the reasons why plants are better than antibiotics, read more about H. pylori and how to treat it using vitamin C and alkalinity.
Other Important Posts:
Yahya, M. F. Z. R., Alias, Z. Karsani, S. A. (2018). Antibiofilm activity and mode of action of DMSO alone and its combination with afatinib against Gram-negative pathogens. Retrieved October 21, 2020 from https://pubmed.ncbi.nlm.nih.gov/28540585/#:~:text=Biofilms%20are%20complex%20microbial%20communities,either%20biotic%20or%20abiotic%20surface.&text=The%20results%20demonstrated%20that%20both,cells%20and%20reducing%20biofilm%20biomass.
Wikipedia (2020). Histamine. Retrieved October 22, 2020 from https://en.wikipedia.org/wiki/Histamine#:~:text=Histamine%20is%20an%20organic%20nitrogenous,as%20a%20mediator%20of%20itching.
Ettinger, M. (2009). The Most Effective Natural H. pylori Treatment Protocol. Retrieved October 21, 2020 from https://www.advancedhealing.com/heartburn-gastritis-achlorhydria-h-pylori/
Rafieian-Kopaei, M. (2016). Treatment of helicobacter pylori infection by herbal drugs; a review on current data. Retrieved October 21, 2020 from http://jprevepi.com/Article/jpe-10
Zanin, T. (2007-2020). What type of diet to follow during H. pylori treatment. Retrieved October 21, 2020 from https://www.tuasaude.com/en/diet-for-h-pylori/
Healthline (2005-2020). What is monolaurin? Retrieved October 21, 2020 from https://www.healthline.com/health/monolaurin#forms-and-doses
Medical News Today (2004-2020). What are the best natural H. pylori treatments? Retrieved October 21, 2020 from https://www.medicalnewstoday.com/articles/322627#natural-treatments
Shahrokhi, N., Keshavarzi, Z., Khaksari, M. (2015). Ulcer healing activity of Mumijo aqueous extract against acetic acid induced gastric ulcer in rats. Retrieved October 22,2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4333629/
Bakare, M. A., Onifade, A. K. (2019). Evaluation of Antimicrobial Activities of Carica papaya, Azadirachta indica, and Moringa oleifera on Helicobacter pylori Isolated from Ulcer Patients in Ondo State, Nigeria. Retrieved October 22, 2020 from https://www.semanticscholar.org/paper/Evaluation-of-Antimicrobial-Activities-of-Carica-on-Bakare-Onifade/7478fb298db1de16afe996e8f599c3a8a8b21220
Shmuely, H., Domniz, N., Yahav, J. (2016). Non-pharmacological treatment of Helicobacter pylori. Retrieved October 22, 2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4848239/
Yahya, M. F., Z. R., Alias, Z., Karsani, S. A. (2018). Antibiofilm activity and mode of action of DMSO alone and its combination with afatinib against Gram-negative pathogens. Retrieved October 22, 2020 from https://pubmed.ncbi.nlm.nih.gov/28540585/#:~:text=Biofilms%20are%20complex%20microbial%20communities,either%20biotic%20or%20abiotic%20surface.&text=The%20results%20demonstrated%20that%20both,cells%20and%20reducing%20biofilm%20biomass.
Rahayunigsih, S. R., Sfitri, R., Andayaningsih, P. (2016). Potency of probiotic bacteria from noni fruit (Morinda citrifolia L.) as anti-Helicobacter pylori agent. Retrieved October 22, 2020 from https://aip.scitation.org/doi/10.1063/1.4953529
Wang, C. K. (2014). Antiadhesion and Anti-inflammation Effects of Noni (Morinda citrifolia) Fruit Extracts on AGS Cells during Helicobacter pylori Infection. Retrieved October 22, 2020 from https://pubmed.ncbi.nlm.nih.gov/24528133/
Lian, D. W., Xu, Y. F., Ren, W. K., Fu, L. J., Chen, F. J., Tang, L. Y., Zhuang, H. L., Cao, H. Y., Huang, P. (2018). Unraveling the Novel Protective Effect of Patchouli Alcohol Against Helicobacter pylori-induced Gastritis: Insights Into the Molecular Mechanism in vitro and in vivo. Retrieved October 24, 2020 from https://pubmed.ncbi.nlm.nih.gov/30524287/
Yang, X., Zhang, X., Yang, S. P., Liu, W. Q. (2013). Evaluation of the Antibacterial Activity of Patchouli Oil. Retrieved October 25, 2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3813264/
Bhaludra, C. S. S. (2014). Comparative Studies on antibacterial activity of patchouli [ Pogostemon cablin ( Blanco ) Benth] and Geranium (Pelorgonium graveolens) aromatic medicinal plants. Retrieved October 25, 2020 from https://www.researchgate.net/publication/271136871_Comparitive_Studies_on_antibacterial_activity_of_patchouli_Pogostemon_cablin_Blanco_Benth_and_Geranium_Pelorgonium_graveolens_aromatic_medicinal_plants
New Directions Aromatics Blog (2017). Patchouli Oil: The History, Benefits, Uses, and More! Retrieved October 25, 2020 from https://www.newdirectionsaromatics.com/blog/products/all-about-patchouli-oil.html#:~:text=There%20are%203%20species%20of,relative%20superiority%20over%20other%20species.
Goswami, S., Bhakuni, R. S., Chinniah, A., Pal, A., Kar, S. K. Das, P. K. (2012). Anti-Helicobacter pylori Potential of Artemisinin and Its Derivatives. Retrieved October 25, 2020 from https://aac.asm.org/content/56/9/4594
(2006). Antibacterial activity of Tabebuia impetiginosa Martius ex DC (Taheebo) against Helicobacter pylori. Retrieved October 25, 2020 from https://pubmed.ncbi.nlm.nih.gov/16359837/
Korona-Glowniak, I., Glowniak-Lipa, A., Ludwiczuk, A., Baj, T., Malm, A. (2020). The In Vitro Activity of Essential Oils against Helicobacter Pylori Growth and Urease Activity. Retrieved October 25, 2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7037374/
Raal, A., Nisuma, K., Meos, A. (2018). Pinus sylvestris L. and other conifers as natural sources of ascorbic acid [Pinus sylvestris L. y otras coniferas como fuentes naturales de ácido ascórbico]. Retrieved October 25, 2020 from https://jppres.com/jppres/pdf/vol6/jppres17.287_6.2.89.pdf
(2018). Vitamin C: A Preventative, Therapeutic Agent Against Helicobacter pylori. Retrieved October 24, 2020 from https://www.cureus.com/articles/13566-vitamin-c-a-preventative-therapeutic-agent-against-helicobacter-pylori
Pal, J., Girija, S. M., Gopal, G. J., Tarsa, U. (2011). Vitamin-C as anti-Helicobacter pylori agent: More prophylactic than curative- Critical review. Retrieved October 25, 2020 from https://www.researchgate.net/publication/51855760_Vitamin-C_as_anti-Helicobacter_pylori_agent_More_prophylactic_than_curative-_Critical_review
Clyne, M., Labigne, A., Drumm, B. (1995). Helicobacter pylori requires an acidic environment to survive in the presence of urea. Retrieved October 25, 2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC173208/
Ierardi, E., Losurdo, G., La Fortezza, R. F., Principi, M., Baroe, M., Di Leo, A. (2019). Optimizing proton pump inhibitors in Helicobacter pylori treatment: Old and new tricks to improve effectiveness. Retrieved October 24, 2020 from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6747288/
Ansari, S., Yamaoka, Y. (2017). Survival of Helicobacter pylori in gastric acid territory. Retrieved October 24, 2020 from https://pubmed.ncbi.nlm.nih.gov/28402047/
Baker, D. A. (2020). Plants against Helicobacter pylori to combat resistance: An ethnopharmacological review. Retrieved October 24, 2020 from https://www.sciencedirect.com/science/article/pii/S2215017X19307222
Healthline (2005-2020). What is Monolaurin? Retrieved October 25, 2020 from https://www.healthline.com/health/monolaurin#:~:text=Side%20effects%20and%20risks,-Although%20the%20FDA&text=The%20only%20risks%20associated%20with,are%20allergic%20to%20tree%20nuts.