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MSM and Dimethylsulfoxide (DMSO) for the Treatment of Dementia

Posted By Jennifer Shipp | Feb 09, 2020

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How to Use DMSO to Treat Dementia

MSM (Methyl Sulfonyl Methane) and DMSO (dimethylsulfoxide) are related compounds that can both help Alzheimer’s and dementia patients return to health. The difference chemically between MSM and DMSO is that MSM contains an extra molecule of oxygen. This is an important difference that changes the way these two substances interact with the human body. While MSM can be found in the grocery store with nutritional supplements  (keep in mind that it’s best to take MSM as a salt at 5 to 10 grams per day, NOT as a capsule – the salt is hard to find in grocery stores), DMSO must be ordered online in liquid form. DMSO is FDA approved and regularly used in the medical industry to store organs for transplantation and as ingredients in things like transdermal patches.   Studies have shown that DMSO alters glutamate and acetylcholine activity in the brain, two neurotransmitters that have been implicated in Alzheimer’s disease. DMSO at a concentration of 1% - 2% delayed paralysis due to Alzheimer’s disease by 48% - 90% respectively. Scientists believe that it has this effect by detoxifying brain cells through the modulation of glutamate and acetylcholine neurotransmitters.

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Using DMSO and MSM as a Natural Treatment for Dementia

  Every cell in the brain needs three things:

  1. Oxygen
  2. A methyl group of molecules
  3. A sulfur group


Both MSM and DMSO provide all three of these key needs to the brain. Both can help reduce swelling and inflammation in the body and they can help get oxygen to brain tissues. DMSO can also regenerate nerve tissues [1]. Dr. Stanley Jacobs in Oregon used DMSO on patients who had severed their spinal columns. One patient with a C5 injury was given DMSO in large doses right after his accident. Not only did he survive, he later walked out of the hospital. 

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DMSO is regularly used in hospitals in Chile.

DMSO and MSM are able to clean toxicities out of cells and spur them to regenerate. This is notable particularly in regards to the ability that these substances have to regenerate nerve and brain tissues. DMSO is able to cross the blood-brain barrier with ease. It is often combined with other medications because DMSO can provide these other meds admittance to brain tissues. DMSO potentiates the medications and it is also sometimes used by oncologists to increase the strength of chemotherapy, thereby making it possible to reduce the dosage of chemo. DMSO has the amazing ability to seek out and destroy microorganisms anywhere in the body while seeking out ailing cells and repairing them at the same time. It goes where it is needed most. 

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In a study published in the journal Neuropharmacology, DMSO was used to restore density to areas of the Central Nervous System and improve memory and behavior in mice [2]. Another study performed in 1970 by Dr. Gustavo Munigazo, Professor of Neurology at Chile University demonstrated that by combining DMSO with amino acids or with vasoactive substances such as Merinex or Ipran, dementia patients showed a remarkable recovery. The study included 104 participants that each belonged to one of the following groups:

  1. Psycho-organic decay caused by cerebro-vascular arteriosclerosis
  2. Psycho-organic decay caused by senility
  3. Psycho-organic decay caused by a stroke
  4. Psycho-organic decay as a consequence of brain injury
  5. Psycho-organic decay due to a degenerative disease such as Parkinson’s disease, hyperthyroidism, epilepsy, or others [4].


A drug called Nilotinib used in conjunction with DMSO has shown promise as a treatment for Parkinson’s disease [5].

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Resources:


[1] CancerTutor (2018). Alzheimer’s and Dementia: Keep Your Brain Alive Part I. Retrieved January 8, 2019 from https://www.cancertutor.com/alz_brainalive/


[2] Penazzi, L., Lorengel, J., Sundermann, F. et al. (2017). DMSO modulates CNS function in a preclinical Alzheimer’s disease model. Retrieved January 8, 2019 from https://www.sciencedirect.com/science/article/pii/S0028390816304749


[3] ScienceBlogs (2007). Alzheimer’s Patch Approved (and a Bit about DMSO). Retrieved January 8, 2019 from https://scienceblogs.com/retrospectacle/2007/07/13/alzheimers-patch-approved-by-t


[4] Walker, M. (1993). DMSO: Nature’s Healer. Retrieved January 8, 2019 from https://www.amazon.com/gp/product/B00I08DMH2/


[5]  Hebron, M. L., Lonskaya, I., Charbel, E. et al. (2013). Nilotinib reverses loss of dopamine neurons and improves  motor behavior via autophagic degradations of a-synclein in Parkinson’s disease models. Retrieved January 8, 2019 from https://watermark.silverchair.com/ddt192.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAjwwggI4BgkqhkiG9w0BBwagggIpMIICJQIBADCCAh4GCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMoU1DfCLXxX8dzQU1AgEQgIIB74OLZsa5al6FgMtSWWeH5o8HWtw_yvFdfgrRaMQaenMjKSbnRi5EweTGYKscHOCcaacnm3hORqmi2_7H4Fvd5rQKV7leSZQagWSVeItpmNIpl190RrDXmX3B4aW8aAGbnAQ08L9Axpon8aFPtYd0lOsNoCksC_dKCSkUxdd49eVzpndIZhIwX6JBcmauPCBv_0yEDx5jTUHE0MpmkDDh0JqVUOb5TqNHJgUcKelNaRD1yTwWfvek5n0hPfEFEKBlUis3YaNARpvB3cCcFu1OOHLiblxPHmzHsvxiuLR0zwrSDpHcmrXt0QGTMwLfrr6QLWgHlSjp-ogcyRfpAVcsTrENuywTT8ChfVDZ1V-Hl3rTSURzNpKjGIIdV0YWoJvpVqD7OzCb_dCfQkH0lqL0e7Ekb-IU0qKL4NNPsi97ye9hvcAMtXolKdl3sx87EYmJItIwua3smaXyzP_Ba8ozVcWgadgyGjKZ91DD8C_TI3vbfKOlbx70ixPXJyrn3FcF2nqZcEL9QOAfsvzIoGupqmwpew1GRkeFPXdPB2Sz530fJFppsvSA2gZtMZ1tyCG8_am2qcu2OK9An5_4Qd6QU3OLzDOgNkT3EdiVno_xoGsnl6w2WXUKZVyc_aSqpEgFKikJcHBRRdrEcG34OppowQ
Sadananda, G. et al. (2021). DMSO Delays Alzheimer’s Disease Causing Aβ-induced Paralysis in C. elegans Through Modulation of Glutamate/Acetylcholine Neurotransmission. Retrieved March 14, 2024 from https://journals.sagepub.com/doi/full/10.1177/09727531211046369

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