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The Tabernaemontana shrub (otherwise known colloquially as Sananga or Xananga) has been used for centuries by certain tribal groups in the Amazon as a natural treatment for cataracts, glaucoma, and other disorders of the eyes. But this is not an herbal treatment that only impacts vision. Sananga worked on all levels to heal the eyes and after one eye-drop, cataract patients are likely to experience intense emotions followed by a sense of profound peace.
Sananga / Xananga is used to heal not only physical, but also ailments of the spirit by clearing the energies and the mind so that the user can experience a new perception and focus on the tasks ahead of them. It has anti-oxidant properties that make it useful on a physical level, but treatment with this medicine is said to extend into other realms too. As an alternative treatment for cataracts, Sananga does not require the patient to undergo surgery, but they may need to travel to gain access to the treatment. Sananga is available in Ecuador and Mexico. People who decide to undergo this treatment should know that it involves intense burning for 5 to 15 minutes. Sometimes the experience is visionary.
Diseases That Can Be Treated with Sananga Eye Drops
Sananga is a powerful medicine with psychoactive properties and it works as an alternative treatment for cataracts, but it’s also been used to treat the following diseases and disorders:
- Myopia (near-sightedness)
- Depth perception issues
- Color perception issues
- Febrifuge (it reduces fevers)
- Emetic (causes vomiting in some instances)
- Anorexia and appetite problems
- Dental problems
- Antidote for snake wounds
- Can be used as a contraceptive
Biologically Important Chemicals Found in Sananga
Because Sananga is made from a plant in the genus Tabernaemontana, each formulation of the drops may contain different ingredients and varying levels of these ingredients. But research has identified the following biologically important chemicals in the plant.
- Coronaridine –
Coronaridine is an allkaloid found in Tabernathe iboga and Tabernaemontana divaricata. Administration of coronaridine to lab rats consistently reduced their self-administration of cocaine and morphine, thus supporting the anecdotal reports that Sananga can be used to treat addictions. Coronaridine also has anti-cancer and anti-tumor effects on the body.
- Quebrachidine –
Quebrachidine is an alkaloid. Alkaloids exhibit a broad range of pharmacological properties. They are anti-cancer (e.g. homoharringtonine aka Omacetaxine Mepesuccinate, a Sigma-Aldrich drug) anti-malarial (e.g. quinine), anti-asthma (e.g. ephidrine), cholinomimetic (e.g. galantamine), analgesic, (e.g. morphine), anti-arrhythmic (e.g. quinidine), vasodilatory (e.g. vincamine), anti-bacterial (e.g. chelerythrine), and anti-hyperglycemic (e.g. piperine). Some have psychotropic effects (e.g. psilocin) or stimulant properties (e.g. cocaine, nicotine, caffeine, theobromine). Some are toxic (e.g. atropine). They are almost uniformly bitter in taste.
- Heyneanine –
This is an alkaloid found in the Tabernaemontana genus that has demonstrated anti-cancer and anti-tumor activity in in vitro studies.
Research on the Tabernaemontana elegans species has shown that 3-Hydroxycoronaridine has strong anti-bacterial properties against both gram-negative and gram-positive bacteria.
- Dregamine –
Studied in the T. elegans plant, dregamine has convulsant properties. It also stimulate respiration and diminishes muscular fatigue. It’s been used to treat muscular and nervous asthenia, respiratory depression and poliovirus type III.
- Aparricine –
This substance, also studied in the T. elegans species, has shown strong activity against poliovirus type III. It demonstrates opioid activity. It also shows promise as an herbal cancer treatment for lymphocytic leukemia.
- Tabernaemontanine –
This substance, also found in T. elegans has a vasodilatory effect that makes it valuable as a potential treatment for arteriosclerosis and cerebral trauma in humans. It also has anti-bacterial activity. Tabernaemontanine has been used to treat human nasopharyngeal epidermoid carcinoma cells. It therefore has some potential as a natural cancer cure.
This is an alkaloid that has demonstrated anti-tumor activity in the Tabernaemontana catharinensis species.
Tabernaemontana undulata vs. Tabernaemontana sananho (kunakip)
The Tabernaemontana sananho species of Sananga (also known as kunakip) is milder than Tabernaemontana undulata. The T. sananho plant has undergone more research than T. undulata and scientists have been able to demonstrate that the T. sananho formulation of Sananga has potent anti-inflammatory properties which supports the idea that it could be an effective treatment for a variety of illnesses from skin infections to arthritis. Many diseases today are caused by or perpetuated by inflammation in the body including even depression (depression and inflammation go together). But in addition to its anti-inflammatory properties, this species of T. sananho Sananga also has anti-microbial properties.
Sananga for Cataracts and Other Diseases of the Eyes
Research on plants of the Tabernaemontana genus have demonstrated that the roots of this plant have the following properties that are relevant to the treatment of cataracts and other diseases:
- Anti-pyretic –
As an anti-pyretic, Sananga can reduce fevers. A 2003 study examined the effects of Tabernaemontana pandacaqui on fevers.
- Anti-inflammatory –
The same 2003 study also demonstrated the anti-inflammatory qualities of T. pandacaqui.
- Antioxidant –
The antioxidant properties of Sananga are particularly relevant to patients suffering from cataracts since free radical damage is one of the most widely recognized causes of cataracts. According to research, the Tabernaemontana genus has strong anti-oxidant properties which benefits the eyes especially (since this medicine is applied directly to the eyes), but it also benefits the body as a whole. Scientists have also speculated that age-related eye problems like macular degeneration may also respond to treatment with Sananga.
- Antimicrobial –
Studies were performed in 1984 and 2002 that showed that T. pachysiphon and T. angulata have anti-microbial properties against a variety of bacteria including Staphylococcus aureus and Pseudomonas aeruginosa, two common infectious organisms that are blamed for drug-resistant eye infections as well as sepsis, and skin and respiratory infections. The anti-microbial properties of this alternative eye infection cure for drug-resistant bacteria is particularly relevant to people who wear contact lenses.
- Anti-fungal –
In 2009, a study demonstrated that extracts of Tabernaemontana stapfiana was an effective treatment against a variety of fungi species including Candida albicans, a yeast that wreak havoc on general health by causing vaginal yeast infections as well as thrush. Anyone who has a compromised immune system can benefit from the anti-fungal properties of sananga.
Research going back as far as 1977 demonstrated that Sananga is a promising natural treatment for cancer. The Tabernaemontana genus that was most effective as an herbal treatment for cancer was T. elegans.
Sananga drops are available for sale here from Psychedelic Times.
Other Important Links:
Weil, A. (2019). Cataracts. Retrieved January 31, 2020 from https://www.drweil.com/health-wellness/body-mind-spirit/vision/cataracts/
Madhua (2020). Sananga. Retrieved January 31, 2020 from http://websitedevelopingdemos.com/madhuanand/en/sananga/
Psychedelic Times (2017). Scientific Studies Hint at How Sananga Eye Drops Treat Ocular Diseases. Retrieved January 31, 2020 from https://psychedelictimes.com/scientific-studies-hint-at-how-sananga-eye-drops-treat-ocular-diseases/
Delorenzi JC, Freire-de-Lima L, Gattass CR, et al. (July 2002). “In vitro activities of iboga alkaloid congeners coronaridine and 18-methoxycoronaridine against Leishmania amazonensis”. Antimicrobial Agents and Chemotherapy. Retrieved January 31, 2020 from https://pubmed.ncbi.nlm.nih.gov/12069962-in-vitro-activities-of-iboga-alkaloid-congeners-coronaridine-and-18-methoxycoronaridine-against-leishmania-amazonensis/
Glick SD, Kuehne ME, Raucci J, Wilson TE, Larson D, Keller RW Jr, Carlson JN (September 1994). “Effects of iboga alkaloids on morphine and cocaine self-administration in rats: relationship to tremorigenic effects and to effects on dopamine release in nucleus accumbens and striatum”. Retrieved January 31, 2020 from https://pubmed.ncbi.nlm.nih.gov/7820611-effects-of-iboga-alkaloids-on-morphine-and-cocaine-self-administration-in-rats-relationship-to-tremorigenic-effects-and-to-effects-on-dopamine-release-in-nucleus-accumbens-and-striatum/
PubChem (2020). Quebrachidine. Retrieved January 31, 2020 from https://pubchem.ncbi.nlm.nih.gov/compound/Quebrachidine
Wikipedia (2020). Heyneanine. Retrieved January 31, 2020 from https://en.wikipedia.org/wiki/Heyneanine
Rizo, W. F. et al. (2013). Cytotoxicity and Genotoxicity of Coronaridine From Tabernaemontana Catharinensis A.DC in a Human Laryngeal Epithelial Carcinoma Cell Line (Hep-2). Retrieved January 31, 2020 from https://pubmed.ncbi.nlm.nih.gov/23569415-cytotoxicity-and-genotoxicity-of-coronaridine-from-tabernaemontana-catharinensis-adc-in-a-human-laryngeal-epithelial-carcinoma-cell-line-hep-2/
Useful Tropical Plants Database (2019). Tabernaemontana elegans. Retrieved January 31, 2020 from http://tropical.theferns.info/viewtropical.php?id=Tabernaemontana+elegans